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Protein supplement twice daily ups strength, lean mass in older men

31 Jul 2017

Protein-based, multi-ingredient nutritional supplements, consumed twice daily, increase lean mass and muscle strength in older males, a new trial has found.

The study included 49 healthy elderly males (mean age 73±1 years; mean body mass index, 28.5±1.5 kg/m2) randomized to receive either the nutritional supplement (n=25) or a control drink (n=24). Participants received supplements or controls alone for the first 6 weeks (phase 1) and underwent an added exercise training for the next 6 weeks (phase 2).

In phase 1, the supplement group showed a 3-percent increase in the sum of all one repetition maximums (1RM) from 206±7kg at baseline to 212±8 kg after 6 weeks (p<0.001). Isotonic muscle strength increased a further 20 percent after phase 2 (p<0.001).

After phase 1, the supplement group showed significant increases in whole-body (0.7 kg; p<0.001), appendicular (0.4 kg; p<0.01), leg (0.3 kg; p<0.01) and trunk (0.4 kg; p=0.002) lean mass. No further increases were observed after phase 2.

No significant changes in strength in the control group was observed during phase 1. Sum of all 1RMs increased by 21 percent (p<0.001) after phase 2. The observed changes in lean body mass in either phase were nonsignificant.

The nutritional supplement used contained whey protein, calcium, omega-3 polyunsaturated fatty acids, creatinine and vitamin D. Control drinks had maltodextrin. Supplements or controls were taken twice daily for 20 weeks.

The exercise regimen consisted of resistance exercise training twice weekly and high-intensity interval training once weekly. Dual-energy x-ray absorptiometry was used to measure body composition.

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Most Read Articles
Elvira Manzano, 4 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
20 hours ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, 22 hours ago
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.