Most Read Articles
3 years ago

Over the past few decades, there has been widespread concern about the increasing proportion of births born by caesarean delivery. The rising rate of primary caesarean section has led to the increased number of obstetric population with a history of prior caesarean delivery. Although this group of women may be offered planned vaginal birth after previous caesarean section (VBAC) or elective repeat caesarean section (ERCS), the VBAC rate is generally low particularly in well-developed countries. In the United States, the VBAC rate has decreased to 8.5% by 2006, while the total caesarean rate has increased to 31.1%.1

one year ago
Kidney and bladder stones (urinary tract stones) are not risk factors for osteoporosis in postmenopausal women, according to the women’s health initiative.
Lianne Cowie, 3 years ago

Tumor necrosis factor (TNF)-α inhibitors are commonly used in the treatment of inflammatory bowel disease (IBD), but the effects of these agents on pregnancy outcomes remain unclear. Now, a systematic review of the English literature has indicated that they pose little risk to the mother or her infant, even if use is continued through the third trimester.

one year ago
A study on participants from the Women's Health Initiative showed the dissociation between calcium/vitamin D supplementation and reduction in menopausal symptoms.

Possible new biomarkers for early prediction of spontaneous preterm birth

11 days ago
Specific miRNA expression profiles have been identified that may enable noninvasive, early prediction of spontaneous preterm birth. If confirmed, such biomarkers could improve infant outcomes by facilitating the identification of women who may benefit from novel and existing therapies aimed at preventing such events.

In the nested, case-control pilot study, researchers used a miRNA array to analyse plasma samples taken from 24 healthy women in their first pregnancy at 20 weeks of gestation who were participants in the New Zealand Cohort of the Screening for Pregnancy End-points (SCOPE) study, and who delivered at term (n=12, controls) or experienced a spontaneous preterm birth at 28–32 weeks (n=12, cases).

Specific miRNA expression profiles that were able to differentiate between cases and controls were identified: miR302B, miR1253, and a cluster of miR548 miRNAs were underexpressed, and miR223 was elevated, among the women with a spontaneous preterm birth compared with the controls.

The researchers suggest that these miRNAs may be attractive candidates as noninvasive biomarkers for early prediction of spontaneous preterm birth, but further larger studies are required to investigate their clinical utility.
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS JPOG - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
3 years ago

Over the past few decades, there has been widespread concern about the increasing proportion of births born by caesarean delivery. The rising rate of primary caesarean section has led to the increased number of obstetric population with a history of prior caesarean delivery. Although this group of women may be offered planned vaginal birth after previous caesarean section (VBAC) or elective repeat caesarean section (ERCS), the VBAC rate is generally low particularly in well-developed countries. In the United States, the VBAC rate has decreased to 8.5% by 2006, while the total caesarean rate has increased to 31.1%.1

one year ago
Kidney and bladder stones (urinary tract stones) are not risk factors for osteoporosis in postmenopausal women, according to the women’s health initiative.
Lianne Cowie, 3 years ago

Tumor necrosis factor (TNF)-α inhibitors are commonly used in the treatment of inflammatory bowel disease (IBD), but the effects of these agents on pregnancy outcomes remain unclear. Now, a systematic review of the English literature has indicated that they pose little risk to the mother or her infant, even if use is continued through the third trimester.

one year ago
A study on participants from the Women's Health Initiative showed the dissociation between calcium/vitamin D supplementation and reduction in menopausal symptoms.