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Persistent wetting in childhood tied to urinary incontinence in adolescence

3 months ago

Persistent wetting during childhood is associated with increased nocturia, bedwetting, daytime wetting, passing hard stools and urgency in adolescence, a new study finds.

The study included 8,751 (4,244 females) children with parent-reported bedwetting and daytime wetting frequency data for at least three of five timepoints: 4, 5, 6, 7 and 9 years of age. Information on bladder and bowel symptoms at age 14 were collected from the participants themselves.

Low stool frequency, passing hard stools, frequent urination, voiding postponement, low voided volume, nocturia, daytime wetting, urgency and bedwetting at age 14 were the primary outcomes of the study.  Parallel longitudinal latent class analysis (LLCA) was performed to create models for daytime wetting and bedwetting.

Five distinct, clinically relevant classes of urinary incontinence were established: normative development of bladder control (n=5,513; 47.5 percent male), delayed attainment of bladder control (n=752; 52.9 percent male), bedwetting alone (n=1,365; 68.4 percent male), daytime wetting alone (n=508; 33.5 percent male) and persistent wetting(n=613; 63.0 percent male).

Those in the daytime wetting alone (odds ratio [OR], 10.1; 95 percent CI, 4.50 to 10.8), persistent wetting (OR, 6.98; 4.50 to 10.8) and delayed bladder control (OR, 4.84; 3.11 to 7.54) classes had increased odds of daytime wetting at 14 years old.

There was an increased chance of bedwetting at 14 years in children that belonged to the persistent wetting (OR, 23.5; 15.1 to 36.5), bedwetting alone (OR, 3.69; 2.21 to 6.17) and delayed bladder control (OR, 3.83; 2.10 to 6.99) groups.

There was also a greater chance of nocturia and urgency in the persistent wetting class (OR, 2.39; 1.79 to 3.20; OR, 2.10; 1.44 to 3.07, respectively). Those in the daytime wetting alone (OR, 2.17; 1.27 to 3.71) and persistent wetting (OR, 2.64; 1.63 to 4.27) classes had greater odds of passing hard stools in adolescence.

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Most Read Articles
25 days ago
In patients with nocturnal urgency secondary to overactive bladder (OAB) and low nocturnal bladder capacity, a mismatch between nocturnal urine production and bladder capacity may predict response to treatment with fesoterodine, according to a study. Symptom improvement appears to be mediated by increases in typical rather than maximum nocturnal voided volumes and be associated with improved quality of life.
one month ago
Compared with subcapsular orchiectomy, 24-week depot triptorelin injections significantly reduce testosterone levels, according to a Danish study.
22 days ago
Older patients with overactive bladder (OAB) appear to have increased frailty compared with individuals seeking care for other nononcologic urologic diagnosis, with frailty being a significant predictor of OAB, a study has found.
19 days ago
The quantity of uric acid stones has significantly increased in recent decades, according to a recent study. There are proportionately more female calcium stone formers but not uric acid stone formers with time. Furthermore, the most prominent factor distinguishing uric acid from calcium stones is urinary pH.