Most Read Articles
Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Tristan Manalac, 2 days ago
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.
15 Oct 2017
Second eye cataract surgery provides greater improvement in visual function and quality of life compared with first eye cataract surgery alone, a recent study claims.

Patients with psoriatic disease have poor sleep quality

27 Sep 2017
Many studies have investigated various risk factors that can contribute to snoring as well as its effects.

Poor sleep quality is not uncommon among patients with psoriatic disease, suggests a recent study. Poor sleep is associated with fatigue, anxiety and lower EQ-5D. It is also associated with actively inflamed joints in patients with psoriatic arthritis (PsA).

A total of 113 PsA and 62 psoriasis without PsA (PsC) patients, as well as 52 healthy controls, were included in this study. Researchers collected clinical variables using a standard protocol. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluated sleep quality.

The investigators also collected other patient-reported outcomes such as the Health Assessment Questionnaire, Dermatology Life Quality Index, EQ-5D, Medical Outcomes Study Short Form-36 survey, patient’s global assessment and the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue scale. Descriptive statistics, Wilcoxon rank-sum test and linear regression were included in the statistical analyses.

The prevalence of poor sleep quality was 84 percent in PsA, 69 percent in PsC and 50 percent in healthy controls. Total PSQI score was higher in both PsA and PsC patients compared with healthy controls (p<0.01). Furthermore, PsA patients had higher PSQI score than PsC patients (p<0.0001).

EQ-5D anxiety component, EQ-5D final and FACIT-fatigue were independently associated with worse PSQI in both PsA and PsC patients (p<0.05). Active joint inflammations (tender or swollen) independently correlated with worse PSQI in patients with PsA (p<0.01).

These results support those in the study by Gezer and colleagues, who found that sleep quality is diminished in patients with PsA. Particularly, sleep disturbance correlated with generalized pain, anxiety and enthesitis, among others, in PsA patients. [Int J Rheum Dis 2014;doi:10.1111/1756-185X]

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Most Read Articles
Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Tristan Manalac, 2 days ago
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.
15 Oct 2017
Second eye cataract surgery provides greater improvement in visual function and quality of life compared with first eye cataract surgery alone, a recent study claims.