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Dr. Maria Katrina Florcruz, 30 Nov 2015
Seven predominantly eczema loci possibly involved in increased risk for atopic march, two of which were previously unidentified, has been identified in a meta-analysis.
Dr. Joslyn Ngu, 07 Jan 2016

A recent study shows cefalexin is effective for treating uncomplicated cellulitis caused by streptococcal species and methicillin-susceptible Staphylococcus aureus (MSSA). [Mayo Clin Proc 2014;89(10):1436–1451]

15 Feb 2016
New drug applications approved by US FDA as of 1 - 15 Feb 2016 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
01 Oct 2010
This study determined the effects of pre-medication with a second generation antihistamine (cetirizine) in urticaria induced by weak COX-1 inhibitors.

Patients with genital melanosis may need careful examinations for melanoma

20 Apr 2017

A careful total body examination may be required in patients with genital melanosis, particularly those with any level of histologic atypia in the genital melanosis lesion, for the possibility of melanoma in any body site, according to a recent study.

To determine the potential risk for genital and nongenital melanoma in patients, a retrospective cohort study was conducted. The authors analysed clinical and histologic data from patients (n=41) with genital melanosis to better describe these lesions and the risk they confer for genital and nongenital melanoma.

Genital melanosis may clinically mimic melanoma, according to researchers. However, its typical age of onset is younger than for genital melanoma.

A majority of lesions stabilized or regressed over time. There were five patients found to have a history of melanoma, one of which was in the genital region. Lesions from these patients were more likely to show melanocytes with suprabasal movement (p=0.0101) and to have a higher melanocyte count (p<0.0462).

This study was limited by the relatively small cohort of patients with an average follow-up of only 30.5 months, researchers said.

A previous study had shown that reflectance confocal microscopy could noninvasively differentiate between vulvar melanoma and vulvar melanosis. Two major features were identified with vulvar melanosis: papillae rimmed by bright monomorphous cells and possible presence of a few dendritic bright cells in the basal layer of the epithelium. Vulvar melanoma was also associated with two major characteristics: atypical cells in the epithelium and loss of normal architecture of chorion papillae. [Dermatol Surg 2012;38:1962-7]

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Most Read Articles
Dr. Maria Katrina Florcruz, 30 Nov 2015
Seven predominantly eczema loci possibly involved in increased risk for atopic march, two of which were previously unidentified, has been identified in a meta-analysis.
Dr. Joslyn Ngu, 07 Jan 2016

A recent study shows cefalexin is effective for treating uncomplicated cellulitis caused by streptococcal species and methicillin-susceptible Staphylococcus aureus (MSSA). [Mayo Clin Proc 2014;89(10):1436–1451]

15 Feb 2016
New drug applications approved by US FDA as of 1 - 15 Feb 2016 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
01 Oct 2010
This study determined the effects of pre-medication with a second generation antihistamine (cetirizine) in urticaria induced by weak COX-1 inhibitors.