Most Read Articles
4 months ago
All patients with acne are potentially at risk of scarring. Professor Goh Chee Leok addresses this issue by focussing on preventing the development of scars in his talk at the 41st Annual Meeting of the Dermatological Society of Malaysia held in Kuching, Sarawak.
18 days ago
CANESTEN HC – Clotrimazole 1% w/w and hydrocortisone 1% w/w cream – Bayer
3 months ago
Olumacostat glasaretil (OG) appears to be effective and is well tolerated in patients with moderate to severe facial acne vulgaris, suggesting the need for further development, according to a new study.
Stephen Padilla, 5 months ago
New topical formulation BiRetix gel Ultra (BR gel) is effective and well tolerated in individuals with mild to moderate acne, reducing both noninflammatory (NI-L) and inflammatory acne lesions (IL), a recent study has found. In addition, BR gel has good skin tolerability and can be considered as first-line treatment for predominant comedonal.

Patients with genital melanosis may need careful examinations for melanoma

9 days ago

A careful total body examination may be required in patients with genital melanosis, particularly those with any level of histologic atypia in the genital melanosis lesion, for the possibility of melanoma in any body site, according to a recent study.

To determine the potential risk for genital and nongenital melanoma in patients, a retrospective cohort study was conducted. The authors analysed clinical and histologic data from patients (n=41) with genital melanosis to better describe these lesions and the risk they confer for genital and nongenital melanoma.

Genital melanosis may clinically mimic melanoma, according to researchers. However, its typical age of onset is younger than for genital melanoma.

A majority of lesions stabilized or regressed over time. There were five patients found to have a history of melanoma, one of which was in the genital region. Lesions from these patients were more likely to show melanocytes with suprabasal movement (p=0.0101) and to have a higher melanocyte count (p<0.0462).

This study was limited by the relatively small cohort of patients with an average follow-up of only 30.5 months, researchers said.

A previous study had shown that reflectance confocal microscopy could noninvasively differentiate between vulvar melanoma and vulvar melanosis. Two major features were identified with vulvar melanosis: papillae rimmed by bright monomorphous cells and possible presence of a few dendritic bright cells in the basal layer of the epithelium. Vulvar melanoma was also associated with two major characteristics: atypical cells in the epithelium and loss of normal architecture of chorion papillae. [Dermatol Surg 2012;38:1962-7]

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Most Read Articles
4 months ago
All patients with acne are potentially at risk of scarring. Professor Goh Chee Leok addresses this issue by focussing on preventing the development of scars in his talk at the 41st Annual Meeting of the Dermatological Society of Malaysia held in Kuching, Sarawak.
18 days ago
CANESTEN HC – Clotrimazole 1% w/w and hydrocortisone 1% w/w cream – Bayer
3 months ago
Olumacostat glasaretil (OG) appears to be effective and is well tolerated in patients with moderate to severe facial acne vulgaris, suggesting the need for further development, according to a new study.
Stephen Padilla, 5 months ago
New topical formulation BiRetix gel Ultra (BR gel) is effective and well tolerated in individuals with mild to moderate acne, reducing both noninflammatory (NI-L) and inflammatory acne lesions (IL), a recent study has found. In addition, BR gel has good skin tolerability and can be considered as first-line treatment for predominant comedonal.