Pain, fatigue are most critical outcomes for patients receiving PsA treatment
The most important outcomes for patients receiving treatment for psoriatic arthritis (PsA) are pain and fatigue, which are not well represented within existing composite measures, suggests a recent study.
Researchers conducted seven nominal group technique (NGT) meetings at four hospital sites to rank outcomes identified as important to patients with PsA and examine their representation in existing composite outcomes. They carried out two sorting rounds to generate a shortlist of outcomes followed by a group discussion and final ranking.
Patients received 15 points each in the final ranking round and then ranked their top five outcomes from the shortlist. The totals were summed across the seven NGT groups and were presented as a percentage of the maximum possible priority score.
A total of 31 patients (mean age 54 years; range, 24 to 77 years; 16 men) participated in the study. The mean disease duration was 10.3 years (range, 1 to 40) and mean Health Assessment Questionnaire was 1.15 (range, 0 to 2.63).
Patients ranked pain (93 points; 20.0 percent) as the highest outcome that they wished to see from treatment. This was followed by fatigue (62 points; 13.3 percent), physical fitness (33 points; 7.1 percent), halting/slowing damage (32 points; 6.9 percent) and quality of life/well-being (29 points; 6.2 percent).
After reviewing existing composite measures for PsA, there was no single measure that adequately identified all these outcomes.
“Future work will focus on validating composite measures modified to identify outcomes important to patients,” researchers said.