Most Read Articles
01 Jun 2015
Long-term oral testosterone undecanoate significantly improved IPSS quality of life scores in a 1-year, randomised, multicentre, double-blind trial among aging hypogonadal men.
Rachel Soon, 01 Jun 2016

The inclusion of statins in managing chronic kidney disease (CKD) may help reduce patient mortality from stroke and possibly other cardiovascular events, according to an expert at the 7th Malaysian Endocrine and Metabolic Society (MEMS) Annual Congress.

Rachel Soon, 01 Jun 2016

Patients with hypercholesterolaemia with unchanging LDL-cholesterol levels after 6 weeks of statin treatment should be actively assessed for either statin intolerance or resistance, says an expert at the 7th Malaysian Endocrine and Metabolic Society (MEMS) Annual Congress.

Prof. Cyrus Rustam Kumana, 07 Jul 2016

This case scenario was presented at a grand round in the Department of Medicine, The University of Hong Kong. Unlike traditional grand rounds that directly or indirectly deal with clinical challenges posed by patients, this one was equally about doctors and how they care for their charges. All doctors who tend patients dread being implicated on the receiving end of medico-legal proceedings. This topic is therefore intimately linked to the professionalism of doctors, their standing in the community, and the ethical aspects of how they interact with patients and relatives.

Mulberry leaf extract lowers postprandial blood glucose

20 Jul 2017
It is a commonly-held assumption that breakfast is the most important meal of the day, but it could inadvertently be doing the body harm.

Mulberry leaf extract (MLE) significantly reduces postprandial blood glucose and is safe at doses of up to 3 grams per day, a new randomized placebo-controlled pilot study shows.

After the 3-month study duration, postprandial self-monitoring blood glucose (SMBG) significantly decreased from baseline in participants who received MLE (n=12; 16.1 percent; p<0.05).

The improvement in postprandial SMBG in the MLE group was also significantly greater when compared with the placebo group (n=12; 18.2 percent; p<0.05).

While baseline systolic (SBP) and diastolic (DBP) blood pressures were significantly greater in the placebo group (150.1±11.60 and 81.4±9.6, respectively) than in the MLE group (130.8±15.38 and 72.2±10.6, respectively; p=0.002 and p=0.035, respectively), there were no significant differences between the two groups at 3 months (p=0.37 and p=0.82, respectively).

Similarly, there were no significant differences in baseline (p=0.13) and 3-month (p=0.44) haemoglobin A1C between the placebo and MLE groups.

There was no significant difference in the incidence of severe or symptomatic hypoglycaemia between the two groups (p=0.36). Two major adverse events were documented in the placebo group. MLE was not shown to be detrimental to body weight, blood pressure or serum marker levels.

The study included 24 patients with controlled type 2 diabetes mellitus and on mono- or oral combination therapy. Exclusion criteria included a history of cardiovascular disease, noncompliance with medication and insulin or alpha-glucosidase inhibitor medication.

There were three phases: a 2-week placebo run-in period, randomization and administration of placebos or MLE, and follow-up at 2 months to assess safety and A1C concentrations. Study outcomes included changes in A1C, pre- and postprandial SMBG and body weight.

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Most Read Articles
01 Jun 2015
Long-term oral testosterone undecanoate significantly improved IPSS quality of life scores in a 1-year, randomised, multicentre, double-blind trial among aging hypogonadal men.
Rachel Soon, 01 Jun 2016

The inclusion of statins in managing chronic kidney disease (CKD) may help reduce patient mortality from stroke and possibly other cardiovascular events, according to an expert at the 7th Malaysian Endocrine and Metabolic Society (MEMS) Annual Congress.

Rachel Soon, 01 Jun 2016

Patients with hypercholesterolaemia with unchanging LDL-cholesterol levels after 6 weeks of statin treatment should be actively assessed for either statin intolerance or resistance, says an expert at the 7th Malaysian Endocrine and Metabolic Society (MEMS) Annual Congress.

Prof. Cyrus Rustam Kumana, 07 Jul 2016

This case scenario was presented at a grand round in the Department of Medicine, The University of Hong Kong. Unlike traditional grand rounds that directly or indirectly deal with clinical challenges posed by patients, this one was equally about doctors and how they care for their charges. All doctors who tend patients dread being implicated on the receiving end of medico-legal proceedings. This topic is therefore intimately linked to the professionalism of doctors, their standing in the community, and the ethical aspects of how they interact with patients and relatives.