Most Read Articles
01 Jul 2013

Acne is particularly prevalent during adolescence, and some teenagers will face an on-going battle with this common skin condition.

01 Apr 2013

Preventing acne and treating oily and acne-prone skin is all about getting back to basics when it comes to products and face-washing routines, a New Zealand pharmacist says.

01 Jul 2013

Acne is a ‘pain,’ as many will attest. It may not be life-threatening, but its impact on quality of life can be great. For the many people who have had to put up with it for a long time, there is frustration and embarrassment, and even anger and depression. Nevertheless, there is hope.

01 Aug 2013

Acne vulgaris (common acne) is the most common skin disease. It is a chronic condition in which there is a blockage or inflammation of hair follicles and the accompanying sebaceous glands.

MKTP delivers long-term repigmentation in vitiligo, other leukodermas

30 Jul 2017

Melanocyte-keratinocyte transplantation procedure (MKTP) confers satisfactory long-term repigmentation in patients with leukoderma, with repigmentation lasting for at least 72 months, reports a recent study.

Researchers conducted a retrospective review of electronic medical records for all MKTPs performed at Henry Ford Hospital between January 2009 and April 2014 to assess long-term repigmentation of MKTP in vitiligo and other leukodermas. A 5-point grading scale (poor to excellent) and Vitiligo Area Scoring Index (VASI) were utilized to evaluate repigmentation.

MKTP was performed at 236 anatomically based lesions (ABLs) in a total of 100 patients, of which 63 with 157 ABLs had available long-term data (12 to 72 months; median 24 months).

VASI scores improved in segmental vitiligo (‒75.6±24.6 percent), nonsegmental vitiligo (‒59.2±36.6 percent) and physical leukoderma (‒32.4±33.5 percent). In vitiligo, 53 percent of ABLs maintained >75 percent repigmentation at 24 months after MKTP, 64 percent at 48 months and 53 percent at 72 months.

Age, skin photoype and anatomic location of ABLs did not show any significant impact on the outcome of treatment.

These results support a previous study, which found MKTP to be effective and well-tolerated based upon categorical and VASI assessments of repigmentation. [J Am Acad Dermatol 2012;66:785-93]

The current study is limited by the retrospective design with uncontrolled, postoperative adjuvant treatments and inconsistent compliance to scheduled follow-up evaluations, according to researchers, adding that persistence of pigmentation after MKTP is a critical consideration for efficacy.

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Most Read Articles
01 Jul 2013

Acne is particularly prevalent during adolescence, and some teenagers will face an on-going battle with this common skin condition.

01 Apr 2013

Preventing acne and treating oily and acne-prone skin is all about getting back to basics when it comes to products and face-washing routines, a New Zealand pharmacist says.

01 Jul 2013

Acne is a ‘pain,’ as many will attest. It may not be life-threatening, but its impact on quality of life can be great. For the many people who have had to put up with it for a long time, there is frustration and embarrassment, and even anger and depression. Nevertheless, there is hope.

01 Aug 2013

Acne vulgaris (common acne) is the most common skin disease. It is a chronic condition in which there is a blockage or inflammation of hair follicles and the accompanying sebaceous glands.