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Meteorological factors tied to occurrence of AD symptoms

9 days ago
Increased evidence-based studies have linked high rates of pollution with strokes and dementia.

Meteorological factors, such as air pollutants, temperature and relative humidity (RH), are associated with atopic dermatitis (AD) symptoms in young children, a new study shows.

The study involved 177 paediatric patients (110 males) with AD who were at most 5 years of age (average 2.0 years). Follow-up period lasted 17 months. Using a smartphone-adjusted diary developed by researchers, parents recorded AD symptoms (oedema, oozing, dryness, erythema, sleep disturbance and itching) and rated them on a scale of 0 to 4.

The database of the Korean Meteorological Association was accessed for data on meteorological factors, including hourly outdoor RH, daily rainfall and hourly outdoor temperature. Ambient air pollution information were retrieved from the National Institute of Environmental Research.

Over the course of the 17-month follow-up, 49.9 and 39.4 percent of boys and girls, respectively, showed symptoms of AD (p<0.0001).

Daily mean RH and temperature were 64.9 percent and 15.0oC, respectively. Mean PM10, NO3 and O3 concentrations were 45.2 µg/m3, 32.4 ppb and 38.1 ppb, respectively. Average rainfall and diurnal temperature range (DTR) values were 2.7 mm/day and 8.9oC, respectively.

An increase of 5oC in outdoor temperature was positively associated with a 12.8-percent (95 percent CI, 10.5 to 15.2 percent) decrease in AD symptoms on the same day. Similarly, an increase of 5 percent in outdoor RH was associated with a 3.3-percent (1.7 to 4.7 percent) decrease in AD symptoms on the same day.

On the other hand, AD symptoms increased by 7.3 percent (3.6 to 11.1 percent) when the amount of rainfall increased by 5 mm on the days that had <40 mm of rainfall. On days that were >14oC DTR, a 5oC increase in DTR was associated with a 284.9-percent (67.6 to 784.2 percent) increase in the risk of AD symptoms.

Finally, the risk of AD symptoms increased by 3.2 percent (1.5 to 4.9 percent), 5.0 percent (1.4 to 8.8 percent) and 6.1 percent (3.2 to 9.0 percent) according to a 10-unit increase in the concentrations of PM10, NO2 and O3, respectively.

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Most Read Articles
Pearl Toh, 5 days ago
Mepolizumab added on to standard of care for patients with severe eosinophilic asthma better improves health-related quality of life (HRQOL), along with improved asthma symptoms and lung function compared with placebo, according to the MUSCA* study.
Pearl Toh, 4 days ago
Treatment with abiraterone acetate and prednisone for metastatic prostate cancer (mPC) in patients who responded poorly to initial androgen-deprivation therapy (ADT) showed encouraging results with favourable overall survival (OS) to historical controls, although the prespecified criteria for a positive result was not met , according to the S1014* trial.
3 days ago
Blood pressure (BP) ≥140/90 mm Hg appears to increase the risk of maternal complications and adverse foetal outcomes, irrespective of the number of medications used, a study suggests. However, the greatest risk is observed among pregnant women taking multiple agents and whose BP levels are within the aforementioned range.
5 days ago
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