Most Read Articles
Elvira Manzano, 4 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, Yesterday
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.

Memory rehabilitation programmes improve memory after left temporal lobe surgery

12 Aug 2017

Memory rehabilitation programmes may improve memory in patients with left temporal lobe epilepsy after surgery, a new study has found.

Eighteen epilepsy patients who had received selective left temporal lobe surgery were designated to receive either active (n=9) or control (n=9) treatment programmes. Active treatment comprised eight weekly hour-long cognitive rehabilitation sessions, which included psycho-education and cognitive techniques for memory and attention.

Objective cognitive outcomes, memory outcomes and functional magnetic resonance imaging (fMRI) were the study outcome measures.

After the cognitive rehabilitation programme, those in the active treatment group showed significant improvements from baseline in the Rey Auditory Verbal Learning Test (45.4±7.4 vs 48.7±6.0; p=0.02), Boston Naming Test (38.3±11.6 vs 42.8±8.2; p=0.02) and Ecological Activity (1 [1 to 3] vs 2 [1 to 3]; p=0.02) scores.

In contrast, only scores in the Ecological Activity significantly improved in the control treatment group (1 [0 to 2] vs 1 [1-2]; p=0.05).

Similarly, self-perception of memory (p=0.008) and strategies used in everyday life (p=0.008) improved significantly after rehabilitation intervention in the active treatment group. No improvements were reported in the control group. Both groups were matched for subjective memory scores at baseline.

Based on fMRI data, significant changes in brain activation in the right anterior prefrontal cortex (Wilcoxon test statistic [W], 1.96; p=0.05), right inferior prefrontal gyrus (W, 2.43; p=0.02) and pars opercularis of Broca’s area in the left hemisphere (W, 2.67; p=0.01) were observed between the first and third scans of the active treatment group.

Activation in the right dorsal anterior cingulate cortex (W, 2.07; p=0.04) and left angular gyrus (W, 2.21; p=0.027) of the active treatment group showed significant changes between the second and third scans.

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Most Read Articles
Elvira Manzano, 4 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, Yesterday
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.