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Maternal refined-grain intake ups risk of overweight, obesity in offspring

19 Jul 2017
It was found that those who consumed a higher intake of whole grains were at a lower risk of heart problems.

Mothers who have high consumption of refined grains during pregnancy are likely to have offspring with higher body mass index z score (BMIZ) and greater risk of overweight or obesity at age 7 years, a recent study has found.

Researchers performed a prospective analysis of refined-grain intake during pregnancy in association with offspring growth through age 7 years among high-risk children born to women with gestational diabetes mellitus (GDM). A total of 918 mother‒singleton child dyads from the Danish National Birth Cohort were included.

Offspring BMIZs were estimated using weight and length or height measured at birth, 5 and 12 months, and 7 years. Researchers used linear and Poisson regressions, adjusting for maternal demographic, lifestyle and dietary factors.

Maternal refined-grain intake during pregnancy positively correlated with offspring BMIZ (adjusted β per serving increase per day, 0.09; 95 percent CI, 0.02 to 0.15) and risk of overweight or obesity at age 7 years (adjusted risk ratio [aRR] comparing the highest with the lowest quartile, 1.80; 1.09 to 2.98; p=0.032 for trend). This association was more evident among children who were breastfed <6 months.

Replacing one serving of refined grains per day with an equal serving of whole grains during pregnancy was associated with a 10-percent reduction in risk of offspring overweight or obesity at age 7 years (aRR, 0.90; 0.82 to 0.98). There were no associations between refined-grain intake and infant growth.

“The findings highlight pregnancy as a potential window of susceptibility associated with offspring growth and obesity risk among this high-risk population,” researchers said. “Data with longer follow-up are warranted.”

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Most Read Articles
Elvira Manzano, 6 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
3 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.