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Smriti Rana, one year ago
Prolonged breastfeeding has a beneficial long term effect on a person’s intelligence quotient (IQ) in adulthood and may be associated with higher levels of education and income potential, a recent study has shown.
Radha Chitale, 3 years ago

Just two of the recommended three doses of human papillomavirus virus (HPV) vaccine may be enough to reduce the risk of condyloma (genital warts) infections and potentially the risk of cervical cancer, a Swedish study has shown.

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Dr Helen Chen, head and senior consultant of the Department of Psychological Medicine at KK Women’s and Children’s Hospital (KKH) in Singapore talks about factors affecting PND and how clinicians can help their patients cope with this condition.
2 years ago
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Low rate of DRMs, vertical transmission of HIV-1 among women treated with Option B+

9 days ago
The 2012 WHO guidelines recommend the initiation of lifelong antiretroviral combination therapy for all pregnant HIV-1 positive women in resource-limited settings regardless of their CD4 count or clinical stage to prevent mother-to-child transmission of HIV-1 (Option B+). There has been some concern that such programmes may encourage the development of drug resistance mutations (DRMs), but a recent study has shown that the risk of drug resistance is low.

A total of 124 HIV-1 positive pregnant women in Fort Portal, Uganda, were enrolled in the study. Blood samples were collected at their first visit to the antenatal clinic before initiating Option B+ as well as at 6 weeks and 6, 12, and 18 months postpartum. Viral load was determined by real-time RT-PCR and analyses were also made of vertical transmission. A total of 49 women (39.5 percent) were also included in a DRM analysis. Virological failure was defined as >1,000 copies HIV-1 RNA/mL.

At 1-year postpartum, three women were found to have virological failure, and seven were affected by the 18-month time point. No vertical transmission of HIV-1 was noted among the 49 mother-infant pairs included in the DRM analysis. However, three women had developed DRMs, and two had dual-class resistance against all recommended first-line drugs.

The researchers suggested that their findings of a low DRM selection rate support the continued adoption of the Option B+ for preventing mother-to-child transmission of HIV-1.
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Most Read Articles
Smriti Rana, one year ago
Prolonged breastfeeding has a beneficial long term effect on a person’s intelligence quotient (IQ) in adulthood and may be associated with higher levels of education and income potential, a recent study has shown.
Radha Chitale, 3 years ago

Just two of the recommended three doses of human papillomavirus virus (HPV) vaccine may be enough to reduce the risk of condyloma (genital warts) infections and potentially the risk of cervical cancer, a Swedish study has shown.

8 months ago
Dr Helen Chen, head and senior consultant of the Department of Psychological Medicine at KK Women’s and Children’s Hospital (KKH) in Singapore talks about factors affecting PND and how clinicians can help their patients cope with this condition.
2 years ago
Anogenital warts, a common sexually transmitted disease, can be effectively cleared with topical nitric oxide delivered using acidified nitrate, according to a multinational group of researchers