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Roshini Claire Anthony, 16 Oct 2017

Treatment failure in osteoporosis remains a problem, even among patients who are treatment-adherent, according to a presentation at the recent meeting of the Asian Federation of Osteoporosis Societies (AFOS 2017), held in Kuala Lumpur, Malaysia. 

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Yesterday
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
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Low-energy diet helps maintain long-term weight loss in obese patients with knee osteoarthritis

18 Sep 2017
You are what you read: To report research findings on studies, in regards to diet and nutrition, accurately, would influence individuals’ choices about what to eat and drink.

The additional use of intermittent low-energy diet (LED) or daily meal replacements after a mean 10-percent weight loss and 1-year maintenance effectively maintains weight loss in obese patients with knee osteoarthritis for 3 years, according to a recent study.

Researchers randomized 153 participants (mean age 63.8 years; mean body mass index, 33.3 kg/m2; 83 percent women) to either the intermittent treatment (IN) group with LED for 5 weeks every 4 months for 3 years (n=76) or to daily meal replacement of one to two meals for 3 years (regular [RE] group; n=77). Attention by dietitians and the amount of formula products were similar.

The participants were recruited between June and December 2009 from the osteoarthritis outpatient clinic at Copenhagen University Hospital in Frederiksberg, Denmark. They had previously completed a 68-week lifestyle intervention trial and lost an average of 10.5 kg or 10 percent of their initial body weight.

Changes in body weight and proportion of participants receiving knee replacements were the primary endpoints, which were analysed on the intention-to-treat population using baseline-carried-forward imputation for missing data.

Of the participants, 53 in the IN group and 56 in the RE group completed the trial. Weight increased by 0.68 kg in the IN group and by 1.75 kg in the RE group (mean difference, ‒1.06 kg; 95 percent CI, ‒2.75 to 0.063; p=0.22). The rates of alloplasty were low and did not differ in both groups (IN group: eight of 76 participants; RE group: 12 of 77 participants; p=0.35).

“These results challenge the commonly held assumption that weight regain in the long term is inevitable,” researchers said.

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Most Read Articles
Roshini Claire Anthony, 16 Oct 2017

Treatment failure in osteoporosis remains a problem, even among patients who are treatment-adherent, according to a presentation at the recent meeting of the Asian Federation of Osteoporosis Societies (AFOS 2017), held in Kuala Lumpur, Malaysia. 

Elvira Manzano, 6 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
2 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.