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Light, moderate alcohol intake may protect against all-cause, CVD death

25 Aug 2017

It appears that light and moderate consumption of alcohol may be protective against all-cause and cardiovascular disease (CVD)-specific mortality, suggests a recent study involving adults in the United States. On the other hand, heavy or binge drinking correlates with elevated risk of all-cause and cancer-specific mortality.

Researchers included a total of 333,247 participants aged ≥18 years. They obtained data by linking 13 waves of the National Health Interview Surveys (1997 to 2009) to the National Heath Index records through 31 December 2011.

Self-reported alcohol intake patterns were classified into six groups: lifetime abstainers; lifetime infrequent drinkers; former drinkers; and current light, moderate or heavy drinkers. Secondary exposure included binge-drinking status of participants. All-cause, cancer or CVD mortality was the main outcome.

Of the participants, 34,754 died of all causes (including 8,947 and 8,427 CVD and cancer deaths, respectively) after a median follow-up of 8.2 years (2.7 million person-years).

Light or moderate alcohol drinkers had a reduced risk of mortality for all causes (light: hazard ratio [HR], 0.79; 95 percent CI, 0.76 to 0.82; moderate: HR, 0.78; 0.74 to 0.82) and CVD (light: HR, 0.74; 0.69 to 0.80; moderate: HR, 0.71; 0.64 to 0.78) compared with lifetime abstainers.

On the contrary, heavy alcohol consumers had a significantly increased risk of mortality for all cause (HR, 1.11; 1.04 to 1.19) and cancer (HR, 1.27; 1.13 to 1.42). Also, an association existed between binge drinking ≥1 day/week and increased risk of all-cause (HR, 1.13; 1.04 to 1.23) and cancer mortality (HR, 1.22; 1.05 to 1.41).

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Most Read Articles
Elvira Manzano, 6 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
3 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.