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Infants with HCS, HTS at high risk for neurovascular anomalies

20 Mar 2017

Hair collar sign (HCS) and hair tuft of the scalp (HTS) may increase the risk for underlying neurovascular abnormalities in infants, suggests a recent study.

“HCS and HTS are cutaneous signs of an underlying neuroectodermal defect, but most available data are based on case reports,” researchers said.

The authors conducted a 10-year multicentre retrospective and prospective analysis of clinical, radiologic and histophathologic features of HCS and HTS in paediatric patients to describe the clinical spectrum of HCS and HTS, clarify the risk for underlying neurovascular anomalies, and provide imaging recommendations.

A total of 78 patients were included in the study. Of these, 56 underwent cranial and brain imaging.

Abnormal findings were identified in 23 of the 56 patients (41 percent). These anomalies included cranial/bone defect (30.4 percent), with direct communication with the central nervous system in 28.6 percent; venous malformations (25 percent); or central nervous system abnormalities (12.5 percent).

The most common neuroectodermal association was meningeal heterotopia in nine of 26 patients (34.6 percent). Also identified were sinus pericranii, paraganglioma and combined nevus.

“Magnetic resonance imaging scans should be performed in order to refer the infant to the appropriate specialist for management,” according to researchers, adding that their study was limited by its partial retrospective design and predominant recruitment from the dermatology department.

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Most Read Articles
6 days ago
Eating red meat may lead to cardiovascular (CV) target organ damage over a 4-year period, according to a recent study involving hypertensive American Indians.
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Magnetoencephalography (MEG) can detect functional network alterations accompanied by amyloid-β (Aβ) deposition in cognitively normal (CN) elderly adults before anatomical changes can be observed, a new study shows.
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