Most Read Articles
Elvira Manzano, 3 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
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Second eye cataract surgery provides greater improvement in visual function and quality of life compared with first eye cataract surgery alone, a recent study claims.
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Hypertension ups risk of rebleeding after TIPSS

27 Aug 2017
29 sources of inaccuracy have been identified in the measurement of adults’ resting blood pressure in clinical settings.

Preascites and hypertension are independent risk factors for parent ascites, while hypertension is an independent risk factor for rebleeding following transjugular intrahepatic portosystemic stent shunt (TIPSS) therapy, a new cohort study has found.

Records of 124 patients who received TIPSS were used in the study. Participants were then divided into two groups: elderly (n=37; age 60 years; 62.6 percent male) and nonelderly (n=87; age <60 years; 73.6 percent male). Exclusion criteria included unsuccessful and emergency TIPSS treatments.

Propensity score matching was performed between the elderly and nonelderly groups to remove potential confounders. The primary outcome was treatment-related adverse events within 1 year. Total length of stay, postoperative hospital stays and hospital deaths were secondary outcomes.

Multivariate logistic regression revealed that hypertension was a significant independent risk factor for rebleeding (odds ratio [OR], 13.249; 95 percent CI, 1.29 to 136.073; p=0.03).

On the other hand, smoking (OR, 4.48; 1.43 to 14.033; p=0.01) and preascites (OR, 6.7; 2.04 to 22.005; p=0.002) were shown as independent risk factors for patients’ ascites following TIPSS treatment.

There were no significant differences between the elderly and nonelderly groups in terms of therapy-related adverse events such as fever (p=0.266), vomiting (p=0.443), bellyaches (p=0.59), diarrhoea (p=0.151), ascites (p=0.393) and rebleeding (p=0.27), suggesting that age was not a significant risk factor for poor outcomes.

“There are limitations to the present study because of its retrospective design. More patients are needed to match more pairs and increase the credibility of the results,” said researchers. 

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Most Read Articles
Elvira Manzano, 3 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
5 days ago
Second eye cataract surgery provides greater improvement in visual function and quality of life compared with first eye cataract surgery alone, a recent study claims.
4 days ago
The size and shape of a person’s face may predict sex drive and intended infidelity, research has shown.