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Elvira Manzano, 2 days ago
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Home-based dialysis tied to reduced health deterioration in elderly patients

17 Sep 2017

Home-based dialysis, regardless of type, appears to reduce the risk of worsening health in older patients, according to a prospective longitudinal cohort study from New Zealand.

Researchers performed a modified Poisson regression analysis to determine the predictors of worse health status in a cohort 150 elderly patients (aged ≥65 years) receiving long-term dialysis. Patient-reported social and health characteristics were evaluated using the 36-Item Short Form Health Survey, EQ-5D and Kidney Symptom Score questionnaires, and clinical information from health records.

The main outcome was health status after 12 months of follow-up, and results showed that 35 percent of the cohort reported worse health or had died at 12 months.

Baseline variables independently associated with reduced risk of worse health status included Pacific ethnicity (relative risk [RR], 0.63; 95 percent CI, 0.53 to 0.72), greater bother on the Kidney Symptom Score (RR, 0.78; 0.62 to 0.97) and dialysis at home (haemodialysis: RR, 0.55; 0.36 to 0.83; peritoneal dialysis: RR, 0.86; 0.79 to 0.93).

On the other hand, baseline variables independently associated with increased risk of worse health status included greater social dissatisfaction (RR, 1.66; 1.27 to 2.17), lower sense of community (RR, 1.70; 1.09 to 2.64), comorbid conditions (RR, 1.70; 1.09 to 2.64), EQ-5D anxiety/depression (RR, 1.61; 1.07 to 2.42), poor/fair overall general health (RR, 1.60; 1.37 to 1.85) and longer dialysis therapy duration (RR, 1.03; 1.00 to 1.05).

Despite the small sample size and restricted study power, the present data should provide encouragement to home-dialyzing patients and their clinicians alike, researchers said.

“Should this finding be confirmed in other countries, this may lead to increased consideration by clinicians and policy makers of more patient-centred home-based dialysis treatment options for older patients with end-stage kidney disease,” they added.

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Most Read Articles
Elvira Manzano, 2 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
07 Oct 2017
Women who follow a low-fat dietary pattern appear to have reduced breast cancer mortality, according to data from the Earlier Women’s Health Initiative Dietary Modification trial.
Pearl Toh, 6 days ago
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
4 days ago
Second eye cataract surgery provides greater improvement in visual function and quality of life compared with first eye cataract surgery alone, a recent study claims.