Most Read Articles
Elvira Manzano, 6 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
3 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.

High waist circumference predicts mortality in peritoneal dialysis patients

06 Sep 2017
Every 4 inches added to a man's waist line translates to a 13 percent risk for prostate cancer.

In peritoneal dialysis (PD) patients, a high waist circumference (WC) and its corresponding increase over time are both significant predictors of mortality, a recent study has found.

Over a 48-month study period, 27 of the 109 patients (mean age 52±16 years; 57 percent male) on PD died. The most common cause of death was cardiovascular disease (n=12). This was followed by sepsis (n=11), infections (n=12), respiratory failure (n=1) and multiple organ failure (n=1). Participants with ascites, hernia or cancers, and those who were on corticosteroids were excluded.

Cox regression analysis showed that high baseline WC (hazard ratio [HR], 71; 95 percent CI, 1.2 to 43.2; p=0.03) and the 6-month increase in WC (HR, 13.6; 2.2 to 83.8; p=0.01) were both significantly correlated with mortality after adjusting for sex, age, diabetes mellitus, time on dialysis, albumin, BMI and C-reactive protein (CRP).

 “The current finding is relevant as available data show that PD patients accumulate body fat over time, particularly in the abdominal area,” said researchers. [Perit Dial Int 1998;18:166-171; Perit Dial Int 2010; 31:67-73]

Along with WC, body weight and height of the participants were also measured; BMI was subsequently calculated. Male participants with >102 cm and female participants with >88 cm WC were designated as high risk participants.

Fasting blood samples were collected and analysed for measurements of serum glucose, albumin and high-sensitivity CRP.

Because high WC and its 6-month increase were both significant predictors of mortality in PD patients, researchers recommended the inclusion of WC monitoring and management in the routine care for patients on PD.

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Most Read Articles
Elvira Manzano, 6 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
3 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.