Most Read Articles
Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, 2 days ago
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.

High prevalence of lower genital tract infection among women in Beijing, China

19 Jul 2017
The prevalence of lower genital tract infection (LGTI) in Beijing is high and that of co-infection is of a magnitude that warrants attention by public health services, according to a recent study.

There has been a notable increase in the incidence of LGTI in recent years, which is of concern since the link between high-risk human papillomavirus (HR-HPV) and other sexually transmitted diseases remains unclear and untreated LGTI such as Chlamydia trachomatis may cause pelvic inflammatory disease, which has been linked to miscarriages, preterm birth, ectopic pregnancy, and tubal factor infertility.

Researchers in China analysed data from 1,218 married women aged 20±70 years who were resident in Beijing for at least 6 months and underwent routine annual gynaecologic health checks between March and October 2014. Cervical secretions and vaginal swab specimens were tested for C. trachomatis, Neisseria gonorrhoeae, Ureaplasma urealyticum, yeast, clue cells, and HR-HPV. The women also completed a structured questionnaire that provided data on demographic status, reproductive health history, sexual behaviour, symptoms of genital tract infection, use of vaginal medications, and use of contraceptive methods.

Laboratory results were available for 1,195 women. Forty-seven percent had LGTI, most commonly U. urealyticum (35.5 percent), bacterial vaginosis (10.5 percent), and yeast infection (3.7 percent). HR-HPV (7 percent) was detected and significantly correlated with abnormal cervical cytology (p<0.0001). Moreover, the risk of HR-HPV infection was significantly increased by the presence of bacterial vaginosis (odds ratio, 3.0, 95 percent confidence interval, 1.7±5.4; p<0.0001).
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Most Read Articles
Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, 2 days ago
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.