Most Read Articles
11 Jun 2015
To help our readers understand more about Japanese encephalitis in Malaysia, JPOG recently sat down with Dr Koh Chong Tuan, consultant paediatrician from Island Hospital, Penang, to get his clinical perspectives on the epidemiology and management of this disease, and how vaccination helps to prevent future outbreaks.
23 Feb 2017
Despite its relative commonness and safety, complementary and alternative medicine does not seem to result in significant positive impacts on the length of hospital stay of patients with bronchiolitis, according to the results of a meta-analysis.
06 Jun 2016

The recent Paediatrics in Practice (PIP) 2016 held recently in Selangor was a success. On top of the launch of a locally published atlas, the conference also featured the introduction of DEBRA (Dystrophic Epidermolysis Bullosa Research Association), various presentations, a workshop and panel discussion on paediatric skin diseases by prominent specialists such as Dr. Tang Jyh Jong, Dr. Tan Wooi Chiang, Dr. Chan Lee Chin, Dr. Sabeera Begum and Dr. Leong Kin Fon. MIMS Doctor spoke to Dr. Thiyagar Nadarajaw, paediatrician and adolescent medicine specialist and Leong, a consultant paediatric dermatologist at the Kuala Lumpur Hospital about the PIP workshop and their thoughts on the atlas.

17 Feb 2017
Musculoskeletal pain at multiple sites among adolescents may be associated with an increased risk of mental health problems, especially mood and anxiety disorders, and mental healthcare use in young adulthood, a study suggests.

Glucomannan delivers limited benefits in children with constipation

13 Jul 2017

Glucomannan may increase the defecation frequency of children with constipation, but it may not have such favourable effects on stool consistency and the rate of successful treatment, according to the results of a systematic review and meta-analysis.

Researchers conducted a comprehensive electronic literature search to identify eligible randomized controlled trials (RCTs) that assessed the effectiveness of glucomannan. The results were reported as mean differences (MDs), standardized mean differences (SMDs) and risk ratios (RRs) with 95 percent CIs.

Defecation frequency per week was the primary outcome, and the secondary outcomes were stool consistency and the rate of successful treatment. The random effects model was used to conduct the meta-analysis.

A total of three RCTs were identified, which involved 122 participants. The use of glucomannan moderately increased the frequency of defecation (3 trials; MD, 1.40; 95 percent CI, 0.36 to 2.44; p=0.008) in children with constipation.

However, no significant differences were observed in the outcomes of stool consistency (3 trials; SMD, 0.48; ‒0.44 to 1.40; p=0.300) or the rate of successful treatment (2 trials; RR, 1.36; 0.48 to 3.81; p=0.110) among participants.

The results of this study should be cautiously interpreted because of the substantial biological, methodological and statistical heterogeneity among the RCTs, according to researchers.

“Additional large-scale, well-designed RCTs on this topic are required,” they said. “The effectiveness and side effects of long-term glucomannan use among children with constipation should be examined in the future in a more systematic manner.”

Constipation is a common complaint among children and significantly affects their quality of life, researchers noted.

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Most Read Articles
11 Jun 2015
To help our readers understand more about Japanese encephalitis in Malaysia, JPOG recently sat down with Dr Koh Chong Tuan, consultant paediatrician from Island Hospital, Penang, to get his clinical perspectives on the epidemiology and management of this disease, and how vaccination helps to prevent future outbreaks.
23 Feb 2017
Despite its relative commonness and safety, complementary and alternative medicine does not seem to result in significant positive impacts on the length of hospital stay of patients with bronchiolitis, according to the results of a meta-analysis.
06 Jun 2016

The recent Paediatrics in Practice (PIP) 2016 held recently in Selangor was a success. On top of the launch of a locally published atlas, the conference also featured the introduction of DEBRA (Dystrophic Epidermolysis Bullosa Research Association), various presentations, a workshop and panel discussion on paediatric skin diseases by prominent specialists such as Dr. Tang Jyh Jong, Dr. Tan Wooi Chiang, Dr. Chan Lee Chin, Dr. Sabeera Begum and Dr. Leong Kin Fon. MIMS Doctor spoke to Dr. Thiyagar Nadarajaw, paediatrician and adolescent medicine specialist and Leong, a consultant paediatric dermatologist at the Kuala Lumpur Hospital about the PIP workshop and their thoughts on the atlas.

17 Feb 2017
Musculoskeletal pain at multiple sites among adolescents may be associated with an increased risk of mental health problems, especially mood and anxiety disorders, and mental healthcare use in young adulthood, a study suggests.