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Frequent ejaculation may prevent prostate cancer in men

07 Jul 2017

More frequent ejaculation in men throughout adult life may help lower the risk of developing prostate cancer, according to a study.

Researchers performed a prospective cohort study of 31,925 men in the Health Professional Follow-up Study using self-reported data on average monthly ejaculation frequency. The participants answered questions on ejaculation frequency on a 1992 questionnaire and followed through to 2010. The authors evaluated the average monthly ejaculation frequency at three time points: age 20 to 29 years, 40 to 49 years and the year before questionnaire distribution.

The main outcome measure was the incidence of total prostate cancer and clinically relevant disease subgroups.

Overall, 3,839 men were diagnosed with prostate cancer during 480,831 person-years. Ejaculation frequency at age 40 to 49 years positively correlated with age-standardized body mass index, physical activity, divorce, history of sexually transmitted infections, and total calories and alcohol intake. All frequency categories showed similar prostate-specific antigen (PSA) test utilization by 2008, number of PSA tests and frequency of prostate biopsy.

Based on multivariable analyses, ejaculation frequency at age 20 to 29 years had a hazard ratio (HR) of 0.81 (95 percent CI, 0.72 to 0.92; p<0.0001 for trend) for the incidence of prostate cancer for ≥21 vs 4 to 7 ejaculations per month; for frequency at age 40 to 49 years, the HR was 0.78 (0.69 to 0.89; p<0.0001 for trend). These associations were driven by low-risk disease, were similar when restricted to a PSA-screened cohort and were unlikely to be explained by competing causes of death.

“These findings provide additional evidence of a beneficial role of more frequent ejaculation throughout adult life in the aetiology of prostate cancer, particularly for low-risk disease,” researchers said.

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Most Read Articles
Elvira Manzano, 4 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
18 hours ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, 20 hours ago
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