Most Read Articles
18 days ago
Regardless of dosing, nonvitamin K antagonist oral anticoagulants (NOACs) are more effective than warfarin for atrial fibrillation and safer in Asian than in non-Asian populations, a new meta-analysis shows.
5 days ago
Nonalcoholic fatty liver diseases (NAFLD) and serum concentrations of alanine transaminase (ALT), aspartate transaminase (AST), gamma-glutamyltransferase (GGT) and alkaline phosphatase (ALP) are independent predictors of incident type 2 diabetes, a new prospective study shows.
4 days ago
There appears to be no evidence supporting associations between physical activity and asthma control level, spirometric measurements and quality of life in children and adolescents with asthma, according to a study from Brazil.
4 days ago
There is a growing number of targeted therapies being approved for use in cancer therapy in the home setting, and this poses a potential risk among family member and caregivers, particularly those of reproductive risk age, a recent study suggests.

Fragility fractures predict CVD events in individuals with rheumatoid arthritis

2 months ago

In men and women with rheumatoid arthritis (RA), fragility fractures are a risk factor for the development of cardiovascular disease (CVD) events and should warn clinicians to target these individuals for further screening and preventive strategies for CVD, suggests a recent study.

To determine whether a fragility fracture is associated with an increased risk of CVD in both women and men with RA, researchers analysed a population-based cohort with incident RA from 1955 to 2007 and compared it with age- and sex-matched non-RA participants. Fragility fractures and CVD events following the RA incidence/index rate were identified, along with relevant predictors.

Cox models were used to examine the link between fractures and the development of CVD, in which fractures and CVD risk factors were modeled as time-dependent covariates.

A total of 1,171 participants (822 women; 349 men) were included in each of the RA and non-RA cohorts. There were 406 and 346 fragility fractures and 286 and 225 CVD events over follow-up, respectively.

A significant increase existed in overall CVD risk for RA participants following a fragility fracture (hazard ratio [HR], 1.81; 95 percent CI, 1.38 to 2.37) but not for non-RA participants (HR, 1.18; 0.85 to 1.63). There were similar results for both women and men with RA.

RA patients are likely to have fragility fractures and CVD, each of which has been reported to increase risks of morbidity and mortality, according to researchers, adding that fragility fractures share similar risk factors for CVD but may occur at relatively younger ages in individuals with RA.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
18 days ago
Regardless of dosing, nonvitamin K antagonist oral anticoagulants (NOACs) are more effective than warfarin for atrial fibrillation and safer in Asian than in non-Asian populations, a new meta-analysis shows.
5 days ago
Nonalcoholic fatty liver diseases (NAFLD) and serum concentrations of alanine transaminase (ALT), aspartate transaminase (AST), gamma-glutamyltransferase (GGT) and alkaline phosphatase (ALP) are independent predictors of incident type 2 diabetes, a new prospective study shows.
4 days ago
There appears to be no evidence supporting associations between physical activity and asthma control level, spirometric measurements and quality of life in children and adolescents with asthma, according to a study from Brazil.
4 days ago
There is a growing number of targeted therapies being approved for use in cancer therapy in the home setting, and this poses a potential risk among family member and caregivers, particularly those of reproductive risk age, a recent study suggests.