Most Read Articles
Elvira Manzano, 3 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
11 hours ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, 13 hours ago
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.

Formula-fed infants gain weight more rapidly, out of proportion to linear growth

12 Aug 2017

Weight gain is quicker and out of proportion to linear growth among formula-fed infants compared with predominantly breastfed ones, a recent study has found.

To investigate the associations of infant feeding with trajectories of growth and body composition from birth to 7 months in healthy infants, researchers analysed 276 participants from a previous study of maternal vitamin D supplementation during lactation. Mothers used monthly feeding diaries to report the extent of breastfeeding.

Researchers measured infants’ anthropometrics and used dual-energy X-ray absorptiometry to evaluate body composition at 1, 4 and 7 months. Changes in infant size (z scores for weight, length and body mass index [BMI]) and body composition (fat and lean mas, body fat percentage) were compared between predominantly breastfed and formula-fed infants, adjusting in linear regression for sex, gestational age, race/ethnicity, maternal BMI, study site and socioeconomic status.

Of the participants, 214 (78 percent) were breastfed (median duration 7 months) and 62 were exclusively formula fed.

Formula-fed, compared with breastfed, infants had lower birth-weight z scores (‒0.22 vs 0.16; p<0.01) but gained more in weight and BMI through 7 months of age (weight z score difference, 0.37; 95 percent CI, 0.04 to 0.71; BMI z score difference, 0.35; 0 to 0.69). There was no difference seen in linear growth (z score difference, 0.05; ‒0.24 to 0.34).

Compared with breastfed infants, formula-fed ones gained more lean mass (difference, 303 g; 137 to 469 g) but not fat mass (difference, ‒42 g; ‒299 to 215 g).

“These differences were attributable to greater accretion of lean mass, rather than fat mass,” researchers said. “Any later obesity risk associated with infant feeding does not appear to be explained by differential adiposity gains in infancy.”

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
Elvira Manzano, 3 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
11 hours ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, 13 hours ago
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.