Most Read Articles
Roshini Claire Anthony, 6 days ago

Treatment failure in osteoporosis remains a problem, even among patients who are treatment-adherent, according to a presentation at the recent meeting of the Asian Federation of Osteoporosis Societies (AFOS 2017), held in Kuala Lumpur, Malaysia. 

Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.

Endoscopic bleeding control improves prognosis of advanced gastric cancer patients

22 Jul 2017

Successful endoscopic bleeding control can help improve survival in bleeding gastric cancer patients, suggests a recent study.

Researchers retrospectively reviewed medical records of 64 patients who underwent endoscopic therapy for gastric cancer bleeding (bleeding group) at Asan Medical Center from January 2012 to December 2014 to determine whether successful bleeding control improves prognosis.

Each patient was matched 1:2 by age, sex and American Joint Committee on Cancer staging with 128 randomly selected patients treated for stomach cancer during the same period (control group). Researchers investigated the rebleeding rate, bleeding treatment methods, median survival and successful bleeding control.

The patients’ median age was 58.5 years, and the male-to-female ratio was 4:3:1. The initial haemostasis rate was 73.4 percent. Single method was used to treat most patients (n=37; 57.8 percent). The most frequently used treatment was the coagrasper (32/95 cases; 33.7 percent).

Seventeen (36.2 percent) of the 47 patients in which successful bleeding control was achieved experienced rebleeding after 3 days. Patients in the control group had longer median survival than those in the bleeding group (18.5 vs 6.5 months).

Furthermore, median survival was also longer in the successful bleeding control than in the failed bleeding control group (8.5 vs 1.8 months). However, patients in the successful bleeding control group had lower survival than those in the control group (18.5 vs 8.5 months).

Based on multivariate analysis, the risk of bleeding was lower in Borrmann type II, IV cancer but was higher in patients using antiplatelet or anticoagulant.

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Most Read Articles
Roshini Claire Anthony, 6 days ago

Treatment failure in osteoporosis remains a problem, even among patients who are treatment-adherent, according to a presentation at the recent meeting of the Asian Federation of Osteoporosis Societies (AFOS 2017), held in Kuala Lumpur, Malaysia. 

Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.