Most Read Articles
Roshini Claire Anthony, 11 Oct 2017

The prevalence of resistant hypertension may be lower than expected, particularly once pseudo-resistant hypertension due to treatment nonadherence is taken into account, according to a presentation at the recent APCH 2017.

Pank Jit Sin, 07 Jan 2015

Cardiovascular diseases (CVD) have been the main cause of death in the Malaysian population since 2007. This trend has continued, with the number of people dying from CVD-related causes increasing year on year. 

Tristan Manalac, 12 Oct 2017
Administration of a long-acting medication at the time that is most suitable for maximum patient compliance is the best approach in controlling blood pressure, said Dr. Trefor Morgan at the recently concluded 13th Asian-Pacific Congress of Hypertension (APCH 2017), held at the Suntec Singapore Convention and Exhibition Centre.
Elaine Soliven, 11 Oct 2017
Reducing daily salt intake is associated with improved blood pressure (BP) levels in patients with hypertension, according to a study presented at APCH 2017.

End-stage renal disease, cardiovascular failure predict extubation failure in obese patients

20 Aug 2017

Cardiovascular system-related respiratory failure, low maximal inspiratory pressure (MIP) and end-stage renal disease (ESRD) are correlated with the risk of extubation failure in obese patients, a new study has found.

Medical records of 595 adult obese patients (mean age 63.6±15.8 years; 67.7 percent male) who required mechanical ventilation and were scheduled for extubation were used in the study. Those without available weight and height data were excluded. Student’s t-test was used to determine the differences between successful and failed extubation cases, while multivariate logistic regression was used to determine variables that predict successful extubation.

Of the patients, 5.7 percent (n=34) experienced failed extubation. The most common cause of failure was haemodynamic instability (n=10). This was followed by excess secretions (n=8), upper airway obstructions (n=8), oxygen failure (n=6) and encephalopathy (n=2).

Those who had failed extubation were significantly older (p=0.004), had higher blood urea nitrogen (p=0.04), more ESRD (p<0.001), less negative MIP (p=0.001) and less positive maximum expiratory pressure (MEP; p=0.001).

Respiratory failure because of cardiovascular system failure (p=0.002) and mortality rates in the intensive care unit (p<0.001) and at 28 days (p<0.001) were also significantly higher in the failed extubation group.

Multivariate logistic regression showed that lower MIP levels (odds ratio [OR], 0.94; 95 percent CI, 0.90 to 0.97; p=0.001), ESRD (OR, 14.0; 6.21 to 31.35; p<0.001) and respiratory failure because of cardiovascular failure (OR, 2.60; 1.16 to 5.80; p=0.02) were significantly tied to higher risks of extubation failure.

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Most Read Articles
Roshini Claire Anthony, 11 Oct 2017

The prevalence of resistant hypertension may be lower than expected, particularly once pseudo-resistant hypertension due to treatment nonadherence is taken into account, according to a presentation at the recent APCH 2017.

Pank Jit Sin, 07 Jan 2015

Cardiovascular diseases (CVD) have been the main cause of death in the Malaysian population since 2007. This trend has continued, with the number of people dying from CVD-related causes increasing year on year. 

Tristan Manalac, 12 Oct 2017
Administration of a long-acting medication at the time that is most suitable for maximum patient compliance is the best approach in controlling blood pressure, said Dr. Trefor Morgan at the recently concluded 13th Asian-Pacific Congress of Hypertension (APCH 2017), held at the Suntec Singapore Convention and Exhibition Centre.
Elaine Soliven, 11 Oct 2017
Reducing daily salt intake is associated with improved blood pressure (BP) levels in patients with hypertension, according to a study presented at APCH 2017.