Most Read Articles
01 Oct 2013

Heart disease is still New Zealand’s biggest killer, with one Kiwi dying from coronary heart disease every 90 minutes. Pharmacy Today New Zealand looks at how pharmacists can help

Pearl Toh, 11 Oct 2017
Clinical practice is an art guided by good science, and clinical practice guideline (CPG) is meant to guide in integrating the art and science of clinical practice for the long-term benefits of patients, said Dr Abdul Rashid Abdul Rahman, a consultant cardiovascular physician at An-Nur Specialist Hospital in Bangi, Malaysia, during the 13th Asian-Pacific Congress of Hypertension (APCH) held in Singapore.
Dr. James Salisi, 01 Jul 2014

The recent spike in the number of new cases of human immunodeficiency virus (HIV) infection in the Philippines means that clinicians and pharmacists alike may need to increase their awareness and competency in prescribing and monitoring HIV treatment. Although taught in medical and pharmacy schools, the scarcity in exposure to clinical cases before highlights the need to for physicians and pharmacist to review HIV pharmacotherapy in order to cater to the increasing HIV patient population.

01 Sep 2017
Complementary medicines can play an important part in maintaining wellness, preventing deficiencies and optimizing health outcomes, says Dr Lesley Braun PhD, Director of the Blackmores Institute. 

Clomiphene citrate improves cycle characteristics, impairs IVF outcomes

06 Sep 2017
 Clomiphene citrate (CC) enhances cycle characteristics but may lead to poorer in vitro fertilization (IVF) outcomes in obese females with polycystic ovarian syndrome (PCOS) undergoing ovarian stimulation for IVF, a recent study has found.

Investigators divided 174 obese women with PCOS undergoing IVF into two groups according to treatments received: those who were given CC with human menopausal gonadotropin (HMG) and medroxyprogesterone acetate (MPA; n=90), and those who received HMG and MPA only (control; n=84).

HMG dose was significantly lower in the HMG+MPA+CC group (1,650 IU) compared with the control group (2,025 IU; p=0.0002038). In contrast, HMG stimulation duration between the two groups were comparable (11 vs 12 days; p=0.077).

The number of oocytes retrieved was significantly higher in the control group than in the study group (13 vs 5; p=0.0000016), while the time from trigger to retrieval of oocytes was comparable between groups.

The control group also had significantly higher numbers of mature oocytes (11 vs 4; p=0.00000386), fertilized oocytes (8 vs 4; p=0.000081) and cleaved embryos (8.5 vs 4 p=0.0000633) compared with the HMG+MPA+CC group.

The number of high quality embryos were also significantly greater in the control group than in the study group (3.5 vs 2; p=0.003).

Recruited participants underwent transvaginal ultrasound to measure antral follicle count and follicle size. Serum concentrations of relevant hormones were also recorded. The primary study outcome was the number of oocytes retrieved, while secondary outcomes included maturation rate, number of high quality embryos and fertilization rate.

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Most Read Articles
01 Oct 2013

Heart disease is still New Zealand’s biggest killer, with one Kiwi dying from coronary heart disease every 90 minutes. Pharmacy Today New Zealand looks at how pharmacists can help

Pearl Toh, 11 Oct 2017
Clinical practice is an art guided by good science, and clinical practice guideline (CPG) is meant to guide in integrating the art and science of clinical practice for the long-term benefits of patients, said Dr Abdul Rashid Abdul Rahman, a consultant cardiovascular physician at An-Nur Specialist Hospital in Bangi, Malaysia, during the 13th Asian-Pacific Congress of Hypertension (APCH) held in Singapore.
Dr. James Salisi, 01 Jul 2014

The recent spike in the number of new cases of human immunodeficiency virus (HIV) infection in the Philippines means that clinicians and pharmacists alike may need to increase their awareness and competency in prescribing and monitoring HIV treatment. Although taught in medical and pharmacy schools, the scarcity in exposure to clinical cases before highlights the need to for physicians and pharmacist to review HIV pharmacotherapy in order to cater to the increasing HIV patient population.

01 Sep 2017
Complementary medicines can play an important part in maintaining wellness, preventing deficiencies and optimizing health outcomes, says Dr Lesley Braun PhD, Director of the Blackmores Institute.