Most Read Articles
2 years ago
Based on a population-based cohort study, pregnant women who underwent assisted reproductive technology, particularly following cryopreservation, are at greater risk for hypertensive disorders.
Kathlin Ambrose, one year ago
The outcome for patients experiencing out-of-hospital sudden cardiac arrest (OSCA) remains very poor in Malaysia. Local data shows that return of spontaneous circulation in OSCA patients stands at 17.4 percent, while survival to ward is a mere 4.3 percent. [Med J Malaysia 2008; 63:4–8]
Christina Lau, 3 years ago

The novel oral anticoagulant (OAC) dabigatran is better than warfarin for stroke prevention in Asian patients with atrial fibrillation (AF), according to a new analysis that included patients from Hong Kong.

one year ago
During the Diabetes Asia 2015 Conference, Professor Jean Claude Mbanya discussed the role of sulphonylureas in today’s management of type 2 diabetes (T2D). Important points from his presentation are summarized below.

Carotid artery reactivity may help assess cardiovascular risk

3 months ago

Lower carotid artery reactivity (CAR%) correlates with older age and cardiovascular risk factors, whereas CAR% demonstrates positive association with coronary artery responses to the cold pressor test (CPT), a recent study has found.

Researchers used ultrasound to measure both resting and peak carotid artery diameters during the CPT, with CAR% being calculated as the relative change from baseline (%). CAR% was compared between young (n=50; 24 ±3 years) and older participants (n=44; 61 ±8 years); the relationships between CAR% and traditional cardiovascular risk factors in 50 participants (44 ±21 years) were also evaluated.

Using transthoracic Doppler echocardiography, a fundamental instrument to understand heart damage during essential arterial hypertension, researchers then compared the left anterior descending (LAD) artery velocity with carotid artery diameter (ie, CAR%) during the CPT (n=33; 37 ±17 years). [J Cardiovasc Med (Hagerstown) 2007;8:997-1006]

CAR% was significantly larger in young compared with older healthy participants (4.1 vs 1.8; p<0.001). Participants with no cardiovascular risk factors showed greater CAR% than those with at least two risk factors (2.9 vs 0.5; p=0.019).

During CPT, both the carotid artery diameter and LAD velocity increased (p<0.001). Carotid diameter (r=0.486; p<0.004) and change in velocity (r=0.402; p<0.02) were both associated with LAD velocity.

“Therefore, CAR% may represent a valuable technique to assess cardiovascular risk, while CAR% seems to reflect coronary artery vasodilator function,” according to researchers.

CAR%, which involves carotid artery diameter responses to a CPT, is a noninvasive measure of conduit artery function in humans, they added.

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Most Read Articles
2 years ago
Based on a population-based cohort study, pregnant women who underwent assisted reproductive technology, particularly following cryopreservation, are at greater risk for hypertensive disorders.
Kathlin Ambrose, one year ago
The outcome for patients experiencing out-of-hospital sudden cardiac arrest (OSCA) remains very poor in Malaysia. Local data shows that return of spontaneous circulation in OSCA patients stands at 17.4 percent, while survival to ward is a mere 4.3 percent. [Med J Malaysia 2008; 63:4–8]
Christina Lau, 3 years ago

The novel oral anticoagulant (OAC) dabigatran is better than warfarin for stroke prevention in Asian patients with atrial fibrillation (AF), according to a new analysis that included patients from Hong Kong.

one year ago
During the Diabetes Asia 2015 Conference, Professor Jean Claude Mbanya discussed the role of sulphonylureas in today’s management of type 2 diabetes (T2D). Important points from his presentation are summarized below.