Most Read Articles
Elvira Manzano, 4 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, Yesterday
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.

BMI, abdominal obesity promote sleep disturbances in postmenopausal women

07 Oct 2017

Both high body mass index (BMI) and abdominal obesity are sources of sleep disturbances in postmenopausal women, negatively affecting deep sleep and sleep efficiency while increasing the risk of obstructive sleep apnoea (OSA), according to a study.

The study included 53 postmenopausal women aged 50 to 70 years from the Ambulatory of Integrative Treatment for Female Sleep Disorders. Of these, 21 were obese (BMI ≥30 kg/m2) and 32 were nonobese (BMI <30 kg/m2). None of the women were receiving hormone therapy.

All participants underwent a full-night polysomnography, with menopause status confirmed by amenorrhea for at least 1 year. Body mass, height, BMI, waist circumference, hip circumference, waist-to-hip ratio (WHR) and neck circumference were also measured.

Results showed that BMI, neck circumference, waist circumference and hip circumference values were significantly greater in the obese vs nonobese group (p<0.01). In contrast, WHR was comparable (p=0.77).

Obese participants specifically had significantly increased values of respiratory disturbance index (16.4 vs 9.3 n[degrees]/h) and apnoea-hypopnea index (14.2 vs 5.6 n[degrees]/h).

Rapid eye movement sleep latency showed a positive correlation with body mass (p<0.01), BMI (p<0.01) and hip circumference (p=0.01). On the other hand, WHR was negatively associated with sleep efficiency (p=0.03).

In a linear regression model, BMI (p<0.01) and WHR (p<0.01) emerged as positive predictors of rapid eye movement sleep latency.

The findings highlight the importance of closely monitoring weight gain and avoiding obesity, especially after menopause, in light of the high prevalence of obesity-related complications that include sleep disorders in postmenopausal women, researchers said.

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Most Read Articles
Elvira Manzano, 4 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, Yesterday
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.