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Bioresorbable implants safe, effective in orbital fracture reconstruction

13 Aug 2017
60% out of 63,000 Malaysians aged 50 years and above who were blind had treatable conditions.

The use of bioresorbable implants appear to be safe and clinically effective in the reconstruction of orbital fractures, reports a recent study.

To assess the clinical effectiveness and safety of various bioresorbable implants in the repair of orbital fractures, researchers retrospectively reviewed patients who had undergone orbital fracture repair with bioresorbable implants in a single tertiary trauma centre from January 2005 to December 2014.

The main outcome measures were improvement in ocular motility, diplopia, enophthalmos and infraorbital hypoaesthesia, as well as complication rates.

In total, there were 94 patients and 98 orbits in this study.

The types of fractures included were as follows: orbital floor blow-out fractures (56.1 percent), zygomaticomaxillary complex fractures (20.4 percent), combined orbital floor and medial wall fractures (15.3 percent) and medial wall blow-out fractures (5.1 percent). For the implants, those evaluated were poly-L/DL-lactide implants (P[L/DL]LA) 85/15 (Rapidsorb), (P[L/DL]LA) 70/30 (PolyMax), polycaprolactone (Osteomesh) and (P[L/DL]LA) 70/30 (MacroPore).

A significant improvement was seen in ocular motility, diplopia, enophthalmos and infraorbital hypoaesthesia postoperatively at week 1, 1 month and 6 months (p<0.001). There was no significant difference between the various implants and types of fractures in postoperative outcome and complications.

Furthermore, late postoperative imaging at 15 to 24 months showed complete resorption of implants and features of neobone formation in all patients.

“Bioresorbable implants offer several advantages over permanent implants and serve as a useful alternative in the reconstruction of orbital fractures,” researchers said.

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Most Read Articles
Elvira Manzano, 4 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Yesterday
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Tristan Manalac, Yesterday
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.