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The treatment armamentarium of atopic dermatitis (AD) includes pharmaceuticals like emollients, topical corticosteroids, and topical calcineurin inhibitors. Recently available, medical devices are a newer class of topical, non-steroidal, semi-solid formulation for the treatment of AD and touted to possess emollient, anti-inflammatory, and anti-pruritic properties. To determine the role of medical devices in flare and remission management in AD, a panel of local experts from the field of dermatology, paediatric dermatology, and allergy convened to review the available evidence and highlights of the meeting are reported here.
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Sexually transmitted infections (STIs) are common, with rates of many infections increas­ing over the last two decades.1 Community screening studies in the UK have shown a prevalence of about 10% for chlamydial infection2 and (among women screened in an urban setting) 3% for gonorrhoea.3 In women (Figure 1), these potentially serious infections are often asymptomatic, whereas the presence of symptoms such as vaginal discharge generally indicates a less pathogenic (but still potentially debilitating) infection, with an organism such as Candida. STIs are often multiple, and the finding of one infection should prompt consider­ation of testing for others. Many sexual health services now initially provide screening tests for asymptomatic women, but a more comprehensive assessment—comprising detailed history4 and genital examination5—is usually necessary when symptoms are present.

Atopic dermatitis shows no correlation with contact sensitization

19 days ago

Current evidence suggests that there is no overall relationship existing between atopic dermatitis (AD) and contact sensitization.

Researchers conducted a systematic review and meta-analysis of the association between AD and contact sensitization. They searched PubMed/Medline, Embase and Cochrane databases for articles that reported on contact sensitization in individuals with and without AD.

A total of 10,083 citations were found. Of these, 417 were selected based on title and abstract screening and 74 met the inclusion criteria of the study.

Pooled analysis revealed that there was no significant difference between AD and controls in contact sensitization (random effects model odds ratio [OR], 0.891; 95 percent CI, 0.771 to 1.03). A positive association existed in studies comparing AD patients with individuals from the general population (OR, 1.50; 1.23 to 1.93). There was, however, an inverse relationship when comparing with referred populations (OR, 0.753; 0.63 to 0.90).

Clinicians should then consider patch testing AD patients when allergic contact dermatitis is suspected, according to researchers.

This study has some limitations. First, articles included in the meta-analysis used different tools to diagnose AD and did not always provide information on current of past disease. Finally, patch test allergens differed between studies.

A 2012 study found that patients with severe AD and asthma have an overall lower prevalence of contact sensitization when compared with controls. On the other hand, mild-to-moderate disease did not suppress contact sensitization. Also, the prevalence of contact sensitization to fragrance chemicals was greater in patients with AD. [Allergy 2012;67:1157-64]

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Most Read Articles
2 years ago
The treatment armamentarium of atopic dermatitis (AD) includes pharmaceuticals like emollients, topical corticosteroids, and topical calcineurin inhibitors. Recently available, medical devices are a newer class of topical, non-steroidal, semi-solid formulation for the treatment of AD and touted to possess emollient, anti-inflammatory, and anti-pruritic properties. To determine the role of medical devices in flare and remission management in AD, a panel of local experts from the field of dermatology, paediatric dermatology, and allergy convened to review the available evidence and highlights of the meeting are reported here.
2 years ago
Hair loss is a common problem for both men and women. Despite the various treatments available, hair loss remains a difficult condition to treat in most people. To gain better insights into the science behind hair loss, an interview was conducted recently with Dr Jia-Wei Liu, member of the European Hair Research Society and Vice President of Research and Development at Legacy Healthcare, Switzerland. The interview focused on hair loss and its management with CG 210TM, a novel botanical hair and scalp essence. 
5 days ago
There is a marked difference in the thickness of the granular layer between palmar psoriasis and hand eczema, and this may be helpful in differentiating between the two skin conditions, according to a recent study.
Jan Welch, 6 years ago

Sexually transmitted infections (STIs) are common, with rates of many infections increas­ing over the last two decades.1 Community screening studies in the UK have shown a prevalence of about 10% for chlamydial infection2 and (among women screened in an urban setting) 3% for gonorrhoea.3 In women (Figure 1), these potentially serious infections are often asymptomatic, whereas the presence of symptoms such as vaginal discharge generally indicates a less pathogenic (but still potentially debilitating) infection, with an organism such as Candida. STIs are often multiple, and the finding of one infection should prompt consider­ation of testing for others. Many sexual health services now initially provide screening tests for asymptomatic women, but a more comprehensive assessment—comprising detailed history4 and genital examination5—is usually necessary when symptoms are present.