Most Read Articles
one year ago
Immediate delivery at 36 weeks has shown to be an ideal delivery approach for women with intrahepatic cholestasis, according to a literature review.
6 months ago

Associate Professor Ng Lee Ching, Director of the Environmental Health Institute (EHI) at the National Environment Agency (NEA), Singapore, speaks about the role of primary care physicians and government agencies in preventing dengue epidemics.

3 days ago
Venlafaxine (VLX) appears to be effective and well-tolerated in patients with neuropathic pain, according to the results of a literature review.
2 months ago
New drug applications approved by US FDA as of 1 - 15 April 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Alcoholic liver disease: Where we are now

2 years ago
Alcoholic liver disease (ALD) is one of the main health problems worldwide, causing millions of deaths each year. The past decades had provided significant progress on the understanding of the onset and progression of ALD. However, there is still no treatment available for ALD, which calls for a novel pathophysiological-targeted therapy. Recent data showed that alcohol consumption induces harmful effects. On the other hand, it was also shown that alcohol can activate several adaptive protective responses to attenuate alcohol-induced liver pathogenesis such as FoxO3, IL-22, autophagy and nuclear lipin-1α. Milk osteopontin seems to protect against ALD, but the role is still controversial. Several clinical trials are ongoing focusing on the harmful effects caused by alcohol consumption. Meanwhile, development of new approaches to target the protective mechanisms induced by alcohol consumption is much anticipated. Better animal models are still needed for the continuing understanding of ALD pathogenesis and for the development of new treatments.
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Most Read Articles
one year ago
Immediate delivery at 36 weeks has shown to be an ideal delivery approach for women with intrahepatic cholestasis, according to a literature review.
6 months ago

Associate Professor Ng Lee Ching, Director of the Environmental Health Institute (EHI) at the National Environment Agency (NEA), Singapore, speaks about the role of primary care physicians and government agencies in preventing dengue epidemics.

3 days ago
Venlafaxine (VLX) appears to be effective and well-tolerated in patients with neuropathic pain, according to the results of a literature review.
2 months ago
New drug applications approved by US FDA as of 1 - 15 April 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.