Most Read Articles
16 Jun 2016
Orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and liraglutide were effective in achieving weight loss among overweight and obese adults at 52 weeks, a recent study found. Phentermine-topiramate and liraglutide were associated with the highest odds of achieving at least 5 percent weight loss.
5 days ago
Intra-articular injections of botulinum toxin-A deliver substantial short-term benefits in terms of pain reduction in patients with refractory joint pain, according to a meta-analysis.
6 days ago
At least one dose of the 13-valent pneumococcal conjugate vaccine (PCV13) has high individual vaccine effectiveness (VE) in preventing invasive pneumococcal disease (IPD) in a paediatric population with suboptimal vaccination coverage, a new study has shown.
Roshini Claire Anthony, 15 Jul 2017

Adding midostaurin to standard chemotherapy appeared to improve overall survival (OS) in patients recently diagnosed with acute myeloid leukaemia (AML) with a FLT3 mutation, according to a recent study.

Alcoholic liver disease: Where we are now

28 Sep 2014
Alcoholic liver disease (ALD) is one of the main health problems worldwide, causing millions of deaths each year. The past decades had provided significant progress on the understanding of the onset and progression of ALD. However, there is still no treatment available for ALD, which calls for a novel pathophysiological-targeted therapy. Recent data showed that alcohol consumption induces harmful effects. On the other hand, it was also shown that alcohol can activate several adaptive protective responses to attenuate alcohol-induced liver pathogenesis such as FoxO3, IL-22, autophagy and nuclear lipin-1α. Milk osteopontin seems to protect against ALD, but the role is still controversial. Several clinical trials are ongoing focusing on the harmful effects caused by alcohol consumption. Meanwhile, development of new approaches to target the protective mechanisms induced by alcohol consumption is much anticipated. Better animal models are still needed for the continuing understanding of ALD pathogenesis and for the development of new treatments.
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Most Read Articles
16 Jun 2016
Orlistat, lorcaserin, naltrexone-bupropion, phentermine-topiramate, and liraglutide were effective in achieving weight loss among overweight and obese adults at 52 weeks, a recent study found. Phentermine-topiramate and liraglutide were associated with the highest odds of achieving at least 5 percent weight loss.
5 days ago
Intra-articular injections of botulinum toxin-A deliver substantial short-term benefits in terms of pain reduction in patients with refractory joint pain, according to a meta-analysis.
6 days ago
At least one dose of the 13-valent pneumococcal conjugate vaccine (PCV13) has high individual vaccine effectiveness (VE) in preventing invasive pneumococcal disease (IPD) in a paediatric population with suboptimal vaccination coverage, a new study has shown.
Roshini Claire Anthony, 15 Jul 2017

Adding midostaurin to standard chemotherapy appeared to improve overall survival (OS) in patients recently diagnosed with acute myeloid leukaemia (AML) with a FLT3 mutation, according to a recent study.