Most Read Articles
Roshini Claire Anthony, 6 days ago

Treatment failure in osteoporosis remains a problem, even among patients who are treatment-adherent, according to a presentation at the recent meeting of the Asian Federation of Osteoporosis Societies (AFOS 2017), held in Kuala Lumpur, Malaysia. 

Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.

Acute non-CV illness in CICU patients tied to mortality, increased length of stay

21 Apr 2017

Acute noncardiovascular illnesses are common in many patients in the modern cardiac intensive care unit (CICU) and are associated with mortality and increased length of stay (LOS), reports a new study.

Researchers analysed 1,042 admissions between 12 October 2013 and 28 November 2014 to the CICU at the University of Virginia Health System, a tertiary-care academic medical centre in the US to determine the relationship of acute noncardiovascular illnesses with outcomes, such as LOS, mortality and hospital readmission.

Acute coronary syndrome (ACS; 25 percent), consisting of both non‒ST-segment elevation ACS (14 percent) and ST-segment elevation myocardial infarction (11 percent), was the most frequent primary diagnosis.

The most common noncardiovascular primary diagnosis was sepsis (5 percent), but it only occurred in 16 percent of all admissions. Acute kidney injury and acute respiratory failure each occurred in 30 percent of admissions. Acute respiratory failure, acute kidney injury or sepsis occurred in 50 percent of all admissions (n=524).

The median LOS in the CICU was 2 days (interquartile range [IQR], 1 to 5 days) and in the hospital 6 days (IQR, 3 to 11 days). Mortality in the CICU and the hospital was 7 and 12 percent, respectively. A total of 920 patients survived to hospital discharge, of which 171 (19 percent) were readmitted within 30 days.

Sepsis, acute kidney injury and acute respiratory failure were all linked to mortality. Acute kidney injury, acute respiratory failure and new-onset subclinical atrial fibrillation (occurring in 8 percent of all admissions) correlated with CICU LOS.

Noncardiovascular illnesses have become more prevalent 50 years since the inception of the CICU, and these may contribute to morbidity and mortality, according to researchers.

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Most Read Articles
Roshini Claire Anthony, 6 days ago

Treatment failure in osteoporosis remains a problem, even among patients who are treatment-adherent, according to a presentation at the recent meeting of the Asian Federation of Osteoporosis Societies (AFOS 2017), held in Kuala Lumpur, Malaysia. 

Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.