Most Read Articles
Pearl Toh, 7 days ago
Mepolizumab added on to standard of care for patients with severe eosinophilic asthma better improves health-related quality of life (HRQOL), along with improved asthma symptoms and lung function compared with placebo, according to the MUSCA* study.
Pearl Toh, 6 days ago
Treatment with abiraterone acetate and prednisone for metastatic prostate cancer (mPC) in patients who responded poorly to initial androgen-deprivation therapy (ADT) showed encouraging results with favourable overall survival (OS) to historical controls, although the prespecified criteria for a positive result was not met , according to the S1014* trial.
5 days ago
Blood pressure (BP) ≥140/90 mm Hg appears to increase the risk of maternal complications and adverse foetal outcomes, irrespective of the number of medications used, a study suggests. However, the greatest risk is observed among pregnant women taking multiple agents and whose BP levels are within the aforementioned range.
7 days ago
Relapse after randomization is more likely to occur in patients with severe baseline hallucinations, reports a new study. In addition, the presence of baseline hallucinations is associated with a greater risk of relapse after discontinuation of risperidone vs continued risperidone treatment.

Acute non-CV illness in CICU patients tied to mortality, increased length of stay

8 days ago

Acute noncardiovascular illnesses are common in many patients in the modern cardiac intensive care unit (CICU) and are associated with mortality and increased length of stay (LOS), reports a new study.

Researchers analysed 1,042 admissions between 12 October 2013 and 28 November 2014 to the CICU at the University of Virginia Health System, a tertiary-care academic medical centre in the US to determine the relationship of acute noncardiovascular illnesses with outcomes, such as LOS, mortality and hospital readmission.

Acute coronary syndrome (ACS; 25 percent), consisting of both non‒ST-segment elevation ACS (14 percent) and ST-segment elevation myocardial infarction (11 percent), was the most frequent primary diagnosis.

The most common noncardiovascular primary diagnosis was sepsis (5 percent), but it only occurred in 16 percent of all admissions. Acute kidney injury and acute respiratory failure each occurred in 30 percent of admissions. Acute respiratory failure, acute kidney injury or sepsis occurred in 50 percent of all admissions (n=524).

The median LOS in the CICU was 2 days (interquartile range [IQR], 1 to 5 days) and in the hospital 6 days (IQR, 3 to 11 days). Mortality in the CICU and the hospital was 7 and 12 percent, respectively. A total of 920 patients survived to hospital discharge, of which 171 (19 percent) were readmitted within 30 days.

Sepsis, acute kidney injury and acute respiratory failure were all linked to mortality. Acute kidney injury, acute respiratory failure and new-onset subclinical atrial fibrillation (occurring in 8 percent of all admissions) correlated with CICU LOS.

Noncardiovascular illnesses have become more prevalent 50 years since the inception of the CICU, and these may contribute to morbidity and mortality, according to researchers.

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Most Read Articles
Pearl Toh, 7 days ago
Mepolizumab added on to standard of care for patients with severe eosinophilic asthma better improves health-related quality of life (HRQOL), along with improved asthma symptoms and lung function compared with placebo, according to the MUSCA* study.
Pearl Toh, 6 days ago
Treatment with abiraterone acetate and prednisone for metastatic prostate cancer (mPC) in patients who responded poorly to initial androgen-deprivation therapy (ADT) showed encouraging results with favourable overall survival (OS) to historical controls, although the prespecified criteria for a positive result was not met , according to the S1014* trial.
5 days ago
Blood pressure (BP) ≥140/90 mm Hg appears to increase the risk of maternal complications and adverse foetal outcomes, irrespective of the number of medications used, a study suggests. However, the greatest risk is observed among pregnant women taking multiple agents and whose BP levels are within the aforementioned range.
7 days ago
Relapse after randomization is more likely to occur in patients with severe baseline hallucinations, reports a new study. In addition, the presence of baseline hallucinations is associated with a greater risk of relapse after discontinuation of risperidone vs continued risperidone treatment.