Spinal fractures are often the result of underlying osteoporosis. Radha Chitale spoke with Dr. Hee Hwan Tak, medical director and senior consultant at the Pinnacle Spine & Scoliosis Centre at Mount Elizabeth Medical Centre, about managing osteoporotic spinal fractures in primary care.
Fractures are a common result of trauma. Associated osteoporosis and overuse injuries can also result in fractures. The fracture pattern depends on the magnitude of the force, duration and direction, and the rate at which it acts. A fracture occurs when the stress applied exceeds the plastic strain of the bone and goes beyond its yield point.
Osteoarthritis (OA) is a degenerative form of arthritis and is the most common type of arthritis today. It involves all the weight-bearing joints of the body, as well as often-used joints like the hands and the spine. OA of the spine is generally referred to as spondylosis.
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.