Global postural re-education (GPR) can moderately improve pain and function in spinal disorders especially when performed during intermediate follow-ups instead of immediately after initial treatment, a new meta-analysis reports.
Combination therapy with methotrexate (MTX) and adalimumab, a human anti–tumour necrosis factor α monoclonal antibody, is effective in the treatment of juvenile idiopathic arthritis (JIA)-associated uveitis, according to a recent report.
Levels of interleukin (IL)-6 in the synovial fluid has significant diagnostic value for prosthetic joint injuries (PJI), especially in periprosthetic infections in the hip and knee, reports a new meta-analysis. Moreover, serum IL-6, although less sensitive, has high specificity and may also help diagnose prosthetic failure.
Celecoxib is preferred over naproxen when added to proton-pump inhibitor (PPI) for preventing recurrent upper gastrointestinal (GI) bleeding in patients at high risk of both GI and cardiovascular (CV) events, who require concomitant aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), according to the CONCERN* study.
Enteric-coated mycophenolate sodium appears to be more effective than azathioprine at inducing long-term clinical remission and preventing relapse in patients with active systemic lupus erythematosus, according to the results of an open-label trial.
New drug applications approved by US FDA as of 16 - 30 April 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
An individually tailored, progressive stretching and strengthening hand exercise programme appears to be a useful adjunct to the medical management of rheumatoid arthritis (RA) patients with hand problems, although the beneficial effects of the programme are diminished over time as patients perform less exercises, according to the results of an extended follow-up of the Stretching and Strengthening for Rheumatoid Arthritis of the Hand (SARAH) trial.
Erectile dysfunction may potentially be associated with gout, a new systematic report and meta-analysis reveals. However, the low quality and high degree of heterogeneity among the studies included reduce the certainty of this conclusion.
Patients with juvenile-onset systemic lupus erythematosus (jSLE) have a higher frequency of renal involvement, cutaneous symptoms, oral ulcers, neuropsychiatric (NP) manifestations, autoimmune hemolytic anaemia (AIHA) and anti-dsDNA positivity than those with adult-onset SLE (aSLE), a recent study has found.
At the International Osteoporosis Foundation Regionals – 6th Asia-Pacific Osteoporosis Meeting in Singapore, Professor Olivier Bruyère shared about the algorithm for the management of knee OA by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). MIMS Doctor also spoke to Professor Jean-Yves Reginster, president of ESCEO about this algorithm and the role of SYSADOAs in the control of pain and prevention of disease progression.