Lung volume is significantly higher in acromegaly patients than in controls, a new cross-sectional study of a large cohort has shown. Subclinical airway obstruction appears to be also present in female patients.
High free sugar intake during pregnancy was associated with a heightened risk of allergy and allergic asthma in the children, independent of their sugar intake during early childhood, according to the ALSPAC* study.
Vitamin D supplementation during pregnancy positively influences the immune system of the neonate, with the modified immune system potentially being better equipped to protect the host against pathogenic infections, according to a study.
Increasing obstructive sleep apnoea (OSA) severity appears to have an independent association with retinal arteriolar narrowing and attenuated vascular pulsation amplitude, with the retinal vasculature a potential surrogate biomarker of cerebral and systemic vascular risk in patients with OSA, according to a study.
Early mechanical cardiopulmonary resuscitation (CPR) with a LUCAS 2 device administered by emergency ambulance crew in patients with out-of-hospital cardiac arrest (OHCA) resulted in improved survival compared with manual CPR, results from the MECCA* study showed.
One-third of dementia cases globally can be prevented by addressing nine lifestyle factors at different stages of life, beginning from better education during childhood, according to a report from The Lancet Commission on Dementia Prevention, Intervention, and Care.
New drug applications approved by US FDA as of 1 - 15 August 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
In patients with chronic obstructive pulmonary disease (COPD), a 6-week programme of online-supported pulmonary rehabilitation (PR) produces positive effects on 6-minute walk test distance and symptom scores that are similar to those achieved with a conventional PR model delivered in face-to-face sessions, a study has shown.
There is, on average, an improvement in dyspnoea, walking distance and quality of life (QoL) during the year after a first episode of pulmonary embolism, particularly during the first 3 months, according to a recent study. However, there are also several clinical and physiological predictors of attenuated improvement over time, such as female sex, higher body mass index (BMI) and exercise limitation on 1-month cardiopulmonary exercise test.
There appears to be no evidence supporting associations between physical activity and asthma control level, spirometric measurements and quality of life in children and adolescents with asthma, according to a study from Brazil.
Peak nasal inspiratory flow is as favourable as formal rhinomanometry as a marker of objective nasal patency but is cheaper, simpler, and more appropriate for serial measurements and home use according to a review.
Inappropriate prescription of anaerobic antibiotics to intensive care unit (ICU) patients admitted with pneumonia frequently occurs, with the prescription associated with prolonged length of stay (LOS) in the ICU, a study has found.