Top Medical News
Pearl Toh, 2 days ago
Targeting mast cells with imatinib, which inhibits the receptor tyrosine kinase KIT, may decrease airway hyperresponsiveness and improve symptoms in patients with severe, poorly controlled asthma, according to a proof-of-principle clinical trial.
2 days ago
The risk of respiratory syncytial virus hospitalization (RSVH) and respiratory-related illness hospitalization (RIH) does not significantly differ between the first and second year of life in paediatric patients with haemodynamically significant congenital heart disease (HSCHD), a new study shows.
Pearl Toh, 3 days ago
The next-generation ALK inhibitor brigatinib yielded high and durable responses in both whole-body and intracranial endpoints, with a median progression-free survival (PFS) of over 1 year in patients with ALK-positive non-small cell lung cancer (NSCLC) whose disease had progressed after crizotinib, according to the ALTA* trial.
Jairia Dela Cruz, 4 days ago
Control treatment with montelukast may effectively reduce acute exacerbations in preschool children with mild persistent asthma, according to a study from Japan.
5 days ago
Patients with chronic obstructive pulmonary disease (COPD) who remain physically active may be less likely to develop depression and anxiety over time, a study has shown.
Tristan Manalac, 6 days ago
While the incidence rate of acute respiratory distress syndrome (ARDS) in Singapore is comparable to the reported values in Europe, the compliance with protective ventilation parameters was inadequate, a new observational study reports.
Jairia Dela Cruz, 9 days ago
Strength exercises with both arms raised above the shoulders pose a serious challenge to patients with chronic obstructive pulmonary disease (COPD) compared with other exercise variations, a study has found. Double-arm elevation above shoulder level particularly increases symptoms and cardiovascular demand, as well as delays heart rate (HR) recovery.
Special Reports
13 Jun 2017
The common cold is one of the most widespread illness and is a leading cause of visits to the doctor and absenteeism from school and work. While many may see it as merely a harmless inconvenience, the significant repercussions it brings, especially among children cannot be denied. MIMS JPOG recently spoke to Associate Professor Datin Dr Asmiati Abd Hamid to gain her perspectives on the role of zinc and vitamin C in treating paediatric common cold to reduce morbidity and economic losses attributed to the condition.
Prof. Ignatius Ou Sai Hong, Dr. James Suh, Dr. Wong Seng Weng, Dr. Amit Verma, 14 May 2017
As targeted cancer therapy options are increasing, it is becoming more important to choose the most appropriate treatment for patients with cancer. At a Roche-sponsored symposium held during the 2nd ESMO Asia Congress in Singapore, four experts discussed the potential of comprehensive genomic profiling (CGP) for personalizing cancer care and helping healthcare professionals to make the best treatment decisions for individual patients.
28 Apr 2017
Idiopathic pulmonary fibrosis (IPF) is a disease marked by scarring and hardening of lung tissues. As a result, the lungs are unable to take in oxygen normally, which leads to lack of oxygen in the bloodstream, causing functional impairment and disability.1 Respiratory medicine experts, Professor Dr Paul W. Noble and Professor Dr Liam Chong Kin recently spoke to MIMS Doctor on IPF diagnosis and treatment. Here are the highlights from the interview.
12 Apr 2017
ESBRIET – Pirfenidone 267 mg hard cap – Roche
01 Mar 2017
At the recent Asia Pacific Alliance for the Control of Influenza (APACI) workshop in Kuala Lumpur, MIMS Doctor had the privilege of having an exclusive interview with eminent paediatric infectious disease specialist, Associate Professor Tawee Chotpitayasunondh. This article captures the highlights from our conversation with him.
03 Jan 2017
At a recent dinner symposium, an expert from Belgium presented on the management of allergic rhinitis, with a particular focus on the use of oral H1-antihistamines and intranasal glucocorticosteroids.
16 Dec 2016
KEYTRUDA – Pembrolizumab 100 mg/4 mL soln for inj – Merck Sharp & Dohme
Conference Reports
Pearl Toh, 05 Jun 2017
Benralizumab helps reduce the need for oral corticosteroids by over four folds while maintaining asthma control in adults with severe eosinophilic asthma compared with placebo, according to the ZONDA* study presented at the ATS Conference 2017 in Washington, DC, US.
Pearl Toh, 02 Jun 2017
Almost one in four adults treated with an antibiotic for community-acquired pneumonia (CAP) fails to respond to treatment, a study presented at the ATS Conference 2017 has shown.
Pearl Toh, 01 Jun 2017
An acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is associated with an increased risk of subsequent cardiovascular (CV) events, especially during the first 30 days after AECOPD, in patients with a history of or at-risk of CV disease, according to a post hoc analysis of the SUMMIT* trial presented at the ATS Conference 2017 in Washington, DC, US.
Pearl Toh, 31 May 2017
Obstructive sleep apnoea (OSA) is associated with an increased risk of new-onset atrial fibrillation (AF), particularly in women, according to a study presented at the American Thoracic Society (ATS) Conference 2017 held in Washington, DC, US.
Christina Lau, 10 May 2017

The use of granulocyte colony stimulating-factor (G-CSF) is safe in patients with limited-stage small-cell lung cancer (SCLC) treated with chemoradiotherapy, according to a post hoc analysis of the phase III CONVERT trial presented at the European Lung Cancer Conference (ELCC) 2017.

Christina Lau, 09 May 2017

Treatment with osimertinib significantly improves symptoms in patients with advanced non-small-cell lung cancer (NSCLC), according to new data from the phase III AURA3 trial presented at the European Lung Cancer Conference (ELCC) 2017.

Christina Lau, 09 May 2017

Patients treated with PD-1/PD-L1 checkpoint inhibitors may be at increased risk of immune-related adverse events (irAEs) after receiving seasonal influenza vaccination, a small study presented at the European Lung Cancer Conference (ELCC) 2017 has shown.

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