Patients with stable schizophrenia may benefit from long-term antipsychotic treatment, with a recent meta-analysis finding that continuation of antipsychotics over a 1-year period significantly reduces symptom exacerbation in this population in contrast to a trajectory of continuous symptom exacerbation in patients on placebo.
Hearing loss is associated with an increased prevalence of dementia, according to a Singapore population-based study. Cognitively normal individuals with hearing loss have a twofold risk of developing neurocognitive disorders (mild cognitive impairment [MCI] or dementia).
The novel VMAT2* inhibitor valbenazine (NBI-98854) significantly improved tardive dyskinesia in individuals with schizoaffective disorder, schizophrenia, or mood disorder, and was generally well tolerated with maintenance of psychiatric stability, according to the KINECT 3** study.
Maternal depression and insensitive parenting were independently associated with infant right frontal electroencephalogram (EEG) asymmetry, which has been linked to negative emotion and behavioural difficulties, among infants who spent a substantial amount of time with their mothers, according to data from the GUSTO* longitudinal birth cohort.
Patients with sleep disorders may be at a greater risk of developing hypertension, with the risk particularly pronounced among those who are younger and those with insomnia, according to a cohort study.
A recent study by researchers from the University of Illinois at Chicago, US, shows that patients with social anxiety disorder (SAD), generalized anxiety disorder (GAD) and/or major depressive disorder (MDD) experience problematic sleep and dysregulated cognitive appraisal.
Scores in the total and memory domain of the Everyday Cognition (ECog) scale are associated with neuroimaging biomarkers and neuropsychological tests, a new study shows. Moreover, the ECog can differentiate normally ageing adults from patients with early stage Alzheimer’s disease (AD).
Depression following an acute myocardial infarction (AMI) is associated with increased 1-year mortality risk, although this association appears to be limited to patients with untreated depression, according to data from the TRIUMPH* study said to be the first to document such association.
Improving emotion regulation strategies may be an important interventional measure for children with self-injurious behaviour due to exposure to abuse (ie, sexual, physical or emotional), according to a Singapore study.
New drug applications approved by US FDA as of 15 – 31 May 2015 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.