Use of clarithromycin in the outpatient setting appears to be associated with long-term increases in mortality, a retrospective study has found. Additionally, erythromycin yields a similar, albeit smaller, increase in the said risk.
Bisphosphonate is one of the first-line therapy for treating osteoporosis, but its long-term use should take into account the balance between its antifracture benefit and risk of adverse events such as atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), according to a presentation at the AFOS 2017 Meeting in Kuala Lumpur, Malaysia.
A recent study suggests that discontinuation of dexamethasone premedication after two uneventful infusions or reduction in the dose of dexamethasone paclitaxel premedication are both safe alternatives to high-dose steroid premedications recommended in product labelling.
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.
Treatment with alphalitic and Odyliresin has significantly improved clinical parameters and uroflowmetry, and has substantially reduced adenoma volume and postvoid residual volume, in patients with benign prostatic hyperplasia-related lower urinary tract symptoms at 12 months, according to a recent study.
Use of romosozumab for 12 months prior to alendronate may yield rapid gains in bone mineral density and significantly cut the risk of fracture in high-risk postmenopausal women with osteoporosis compared with alendronate alone, according to the results of a phase III ARCH* trial.
In the primary care setting, multidisciplinary medication-assisted treatment (MAT) approaches that employ integrated clinical teams and home inductions appear to be effective against opioid use disorder (OUD), according to a new meta-analysis.
Ixekizumab, a high-affinity monoclonal antibody that selectively targets interleukin 17A, is safe and effective in moderate-to-severe plaque psoriasis, providing a persistent and long-term clinical response through 108 weeks of treatment, reports a recent study.
One or more relevant drug-drug interactions occur in some lung cancer patients treated with cytotoxic therapy, highlighting the importance of medication surveillance by a hospital pharmacist to prevent possible negative drug-drug interactions, suggests a recent study.
Clinical practice is an art guided by good science, and clinical practice guideline (CPG) is meant to guide in integrating the art and science of clinical practice for the long-term benefits of patients, said Dr Abdul Rashid Abdul Rahman, a consultant cardiovascular physician at An-Nur Specialist Hospital in Bangi, Malaysia, during the 13th Asian-Pacific Congress of Hypertension (APCH) held in Singapore.
The recent spike in the number of new cases of human immunodeficiency virus (HIV) infection in the Philippines means that clinicians and pharmacists alike may need to increase their awareness and competency in prescribing and monitoring HIV treatment. Although taught in medical and pharmacy schools, the scarcity in exposure to clinical cases before highlights the need to for physicians and pharmacist to review HIV pharmacotherapy in order to cater to the increasing HIV patient population.