In foetuses exposed to the anti-Ro/SSA antibody, the rate of recurrence of conduction disturbances is higher than what was previously reported, according to a recent study. Moreover, the season of the year appears to be linked to atrioventricular (AV) time intervals during the congenital heart block risk period in such foetuses.
Having both type 1 diabetes and coeliac disease (CD) autoimmunity in early childhood appears to be more common than expected, with the development of islet autoantibodies (IAs) conferring a significant risk of subsequent tissue transglutaminase autoantibodies (tTGAs), according to data from the TEDDY* study.
Neonatal adiposity is strongly associated with anthropometric measurements such as weight and the weight-to-length ratio (weight/length), according a Singapore study. These measures may then be employed as simple predictors of adiposity.
New drug applications approved by US FDA as of 1 - 15 October 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Continuous glucose monitoring (CGM)-guided glucose titration appears to safely and effectively increase the time spent in the euglycemic range, while reducing the risk of both hypoglycaemia and hyperglycaemia and minimizing glucose variability in preterm infants during the first week of life, according to a study.
Bacillus Calmette-Guérin (BCG) vaccination is not associated with any changes in the risk of developing childhood asthma, suggesting that any associations previously reported may be attributed to confounding factors, according to the QBCIH* study.
Using a reduced computed tomography (CT) dose to diagnose appendicitis in adolescents and young adults does not appear to affect clinical outcomes, and could potentially reduce the long-term risk of radiation-related cancers, according to results of the LOCAT* trial.
Children who have experienced maltreatment may have altered autobiographical memory functioning, which entails reduced activation in areas encoding positive memories, leading to them according heightened salience to negative memories, a study has shown.
Higher body mass index (BMI) in childhood is likely to increase the risk of disordered eating during adolescence, according to a recent study. In addition, binge eating and overeating in males during early adolescence may lead to higher BMI 5 years later.
Intranasal delivery of dry powder glucagon in paediatric type 1 diabetes (T1D) patients with moderate to severe hypoglycaemia appears to induce recovery over half an hour, with the rise in blood glucose occurring within 15 minutes, according to a study presented at the 53rd Annual Meeting of the European Association for the Study of Diabetes (EASD 2017).