In this MIMS Oncology 'Focus on Biosimilars' newsletter, you will find an article explaining the role of biologics and biosimilars, and a case study sharing the experience of using biosimilar filgrastim in peripheral blood stem cell mobilization for haematopoietic stem cell transplantation.
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Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are superior to chemotherapy as first-line therapy for advanced non-small cell lung cancer (NSCLC) with positive EGFR gene mutations in terms of progression-free survival rates, says an expert.
Adjuvant capecitabine therapy significantly improved disease-free survival (DFS) in HER2-negative primary breast cancer patients with residual invasive disease after neoadjuvant chemotherapy (NAC), according to results of the CREATE-X* trial presented at the recent San Antonio Breast Cancer Symposium 2015 in San Antonio, Texas, US.
A study reveals yet another benefit with regular aspirin use, this time showing a reduction in the long-term risk of hereditary colorectal cancer (CRC) in obese patients with Lynch syndrome (LS), a condition caused by mutations in the mismatch repair (MMR) genes.
Pneumonitis is a rare but potentially fatal side effect of immune checkpoint antibodies that target the programmed death-1 receptor and programmed death-ligand 1 [PD-1/PD-L1] pathway, and clinical caution is recommended in order to deliver appropriate urgent treatment.