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Naomi Adam, 2 years ago
Colorectal cancer is one of the leading cancers worldwide and one of the most difficult to treat because patients often present in later, metastatic stages of disease. Preventing blood vessel growth is a popular therapeutic strategy to help reduce the proliferation of cancerous tissue. Aflibercept (Zaltrap®, Sanofi) is a monoclonal antibody treatment that targets the cell signalling pathways of angiogenesis to prevent blood vessel growth in malignancies.
one year ago
A phase III, randomized, multi-center trial showed that dexamethasone helped reduce the incidence of radiation-induced pain flare in the treatment of bone metastases.
one year ago
Patients with advanced, epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) obtain survival benefit from EGFR tyrosine kinase inhibitor (TKI) treatment, a meta-analysis has shown.
Radha Chitale, one year ago
Genetically engineered T cells that target and destroy plasma cells may have the potential to cure patients with advanced multiple myeloma (MM), according to the results of a small, phase I/II trial in which one patient with over 90 percent of bone marrow cells affected was cleared of myeloma 1 month after treatment and researchers say he remains in stringent complete remission. [ASH 2015, abstract LBA 1]