S-1* combination therapy was associated with a higher response rate and longer progression-free survival (PFS) than S-1 monotherapy in patients with gemcitabine-refractory advanced pancreatic cancer, a new meta-analysis has found.
Active surveillance on patients with localized prostate cancer results in a decreased rate of active surveillance failure, prostate cancer specific mortality and metastases regardless of baseline risk, according to a recent study.
Dr Ravichandran Nadarajah, a consultant at the Department of Obstetrics & Gynaecology, Singapore General Hospital, speaks to Roshini Claire Anthony on the significant role played by GPs in ensuring early diagnosis and prevention of cervical cancer.
Women of Malay ethnicity appear to have poorer prognosis for invasive ductal carcinoma (IDC) of the breast compared with women of Chinese and Indian ethnicity, with higher risks of all-cause mortality and breast cancer-related deaths, according to a Singapore study.
In Asian patients with hepatitis C virus (HCV) infection, the genotype 6 infection contributes to an increased risk of hepatocellular carcinoma (HCC), particularly among those with liver cirrhosis, reports a multinational team of investigators.
There are independent patient responses to high-dose interleukin-2 and to targeted agents before and after receiving high-dose interleukin-2, according to a recent study. This suggests that carefully selected patients must be given high-dose interleukin-2 for the possibility of a complete and durable response without the fear of limiting the treatment benefit of targeted agents.
Maintenance therapy with vinflunine in patients with advanced transitional-cell carcinoma of the urothelial tract affords better progression-free survival (PFS) compared with best supportive care alone, with the drug demonstrating an acceptable toxicity profile, according to data from a phase II study.
Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are superior to chemotherapy as first-line therapy for advanced non-small cell lung cancer (NSCLC) with positive EGFR gene mutations in terms of progression-free survival rates, says an expert.
A study reveals yet another benefit with regular aspirin use, this time showing a reduction in the long-term risk of hereditary colorectal cancer (CRC) in obese patients with Lynch syndrome (LS), a condition caused by mutations in the mismatch repair (MMR) genes.
Pneumonitis is a rare but potentially fatal side effect of immune checkpoint antibodies that target the programmed death-1 receptor and programmed death-ligand 1 [PD-1/PD-L1] pathway, and clinical caution is recommended in order to deliver appropriate urgent treatment.