A 55-year-old man presented with almost one year history of heat intolerance, mild palpitation and significant weight loss. Free T3 and T4 were elevated with normal TSH. Patient had suboptimal response to carbimazole therapy.
A 73-year-old man presented with 1 week’s history of progressive epigastric pain. The pain was dull in nature and the patient reported no vomiting or radiation of pain. On presentation, the patient was found to have a low-grade fever (temperature, 37.8°C). There was no tea-coloured urine. The patient had enjoyed good past health except for a previous surgery for spinal injury.
Krukenberg tumour is a metastatic signet ring cell adenocarcinoma of the ovary. This tumour is uncommon, accounting for 1–2% of all ovarian tumours. The stomach is the primary site in most Krukenberg tumour cases (70%), and the prognosis is generally poor. We report a case of a pregnant lady who was incidentally found to have a large ovarian mass during caesarean section which was later confirmed to be a Krukenberg tumour.
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First results from the ALTTO trial (Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization) shows no benefit of adding lapatinib to standard trastuzumab adjuvant therapy in women with human epidermal growth factor receptor 2 (HER2)-positive early breast cancer.
New drug applications approved by US FDA as of 16 - 31 Dec 2015 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Neither a specific diagnostic approach nor “a gender-driven” therapy is currently available for women with lung cancer, according to an expert who discussed existing assumptions and evidence at the recent Asia Pacific Lung Cancer Conference 2016.