Menopausal symptoms, such as vasomotor, joint and urinary, are associated with obesity, a recent study has found. Hot flashes are particularly related to higher body mass index (BMI), urinary urgency and vaginal dryness.
Among patients with polycystic ovary syndrome (PCOS), enlarged ovarian volume and follicle excess are associated with insulin resistance, according to a study. Furthermore, the number of ovarian follicles could be a useful predictor of insulin resistance.
Preconception thyroid stimulating hormone (TSH) elevation, even within the normal nonpregnant range, is associated with increased risk of adverse pregnancy outcomes, according to a population-based cohort study.
Electronic-based (e-based) lifestyle interventions may improve gestational weight gain, postnatal weight loss, control of caloric intake and levels of physical activity, a new meta-analysis shows.However, because of the homogeneity in techniques and the overall lack of studies, the evidence is inadequate for drawing solid conclusions.
Misoprostol is an effective noninvasive method to complete abortion in missed abortions, a new meta-analysis reveals. Moreover, sublingual doses of 600 µg or vaginal doses of 800 µg may potentially be good first doses.
Higher plasma percentages of ω-3 polyunsaturated fatty acids (PUFAs) and a lower ratio of ω-6-to-ω-3 PUFAs in the late-second trimester of pregnancy are predictors of less weight retention at 18 months postpartum, according to a study involving a multiethnic Asian cohort.
Conjugated oestrogens/bazedoxifene (CE/BZA) may reduce hot flush frequency by approximately half after around 8 to 10 days of treatment, according to a posthoc analysis. Sustained improvement can be achieved with continued treatment.
Over the past few decades, there has been widespread concern about the increasing proportion of births born by caesarean delivery. The rising rate of primary caesarean section has led to the increased number of obstetric population with a history of prior caesarean delivery. Although this group of women may be offered planned vaginal birth after previous caesarean section (VBAC) or elective repeat caesarean section (ERCS), the VBAC rate is generally low particularly in well-developed countries. In the United States, the VBAC rate has decreased to 8.5% by 2006, while the total caesarean rate has increased to 31.1%.1
Doppler measurement of cerebroplacental ratio (CPR) can detect chronic placental insufficiency and failure to reach growth potential (FRGP) in appropriate-for-gestational age (AGA) pregnancies. This allows to time delivery of pregnancies, except monochorionic pregnancy, says Dr Tony Tan from the Department of Obstetrics and Gynaecology, Raffles Hospital, Singapore.
As evaluated in a randomised, controlled study on three-year leuprorelin acetate treatment with tamoxifen, it is as safe and effective as two-year therapy in premenopausal, endocrine-responsive breast cancer patients.