Anosmia is associated with abnormalities in neuroimaging measures of amyloid and neurodegeneration that are present in the preclinical stage of Alzheimer’s disease (AD), according to a study. This suggests the potential utility of olfactory assessment for identifying early AD in cognitively normal older adults.
Older adults with increased day-to-day blood pressure (BP) variability may be at greater risk of developing all-cause dementia, vascular dementia and Alzheimer’s disease, according to a Japanese cohort study.
Individuals with Parkinson’s disease of moderate severity experienced improvement in motor symptoms following 48 weeks of treatment with the glucagon-like peptide-1 (GLP-1) receptor agonist exenatide, according to results of a small study.
Individuals who are married or report being very satisfied with life have a lower risk of developing mild cognitive impairment (MCI) and dementia, according to results from the Singapore Longitudinal Ageing Study (SLAS).
The predictors of further attacks in patients being treated for neuromyelitis optica spectrum disorder (NMOSD) are age, antibody status and possible previous attacks, according to recent study. Additionally, azathioprine and rituximab perform better than interferon-β in the treatment of NMOSD.
Transcatheter aortic valve replacement (TAVR) with a self-expanding prosthesis is noninferior to surgical aortic valve replacement (SAVR) in terms of death from any cause or disabling stroke at 2 years in intermediate-risk patients with severe aortic stenosis (AS), according to data from the SURTAVI* trial presented at the ACC.17 held in Washington, DC, US.
Individuals who underwent autologous haematopoietic stem cell transplantation (AHSCT) as a treatment for multiple sclerosis (MS) had improved progression-free survival (PFS) and overall survival (OS) five years post-transplant, a recent retrospective, observational study found.