Anosmia is associated with abnormalities in neuroimaging measures of amyloid and neurodegeneration that are present in the preclinical stage of Alzheimer’s disease (AD), according to a study. This suggests the potential utility of olfactory assessment for identifying early AD in cognitively normal older adults.
Older adults with increased day-to-day blood pressure (BP) variability may be at greater risk of developing all-cause dementia, vascular dementia and Alzheimer’s disease, according to a Japanese cohort study.
Individuals with Parkinson’s disease of moderate severity experienced improvement in motor symptoms following 48 weeks of treatment with the glucagon-like peptide-1 (GLP-1) receptor agonist exenatide, according to results of a small study.
There is limited evidence showing the efficacy of cannabis in alleviating neuropathic pain, but evidence for other types of chronic pain is lacking, according to a systematic review. Evidence is also insufficient with respect to its association with an increased risk for nonserious short-term adverse effects and potentially serious mental health adverse effects, such as psychosis.
One-third of dementia cases globally can be prevented by addressing nine lifestyle factors at different stages of life, beginning from better education during childhood, according to a report from The Lancet Commission on Dementia Prevention, Intervention, and Care.
A new noninvasive intracranial pressure monitoring device (HS-1000) produces comparable results and may protect patients from the risks associated with the invasive monitoring method, according to preliminary findings of a German study.
Stopping statins within 6 months after a first ischaemic stroke was associated with an increased risk of recurrent stroke at 1 year compared with those who continued with the therapy, a new study showed.
People who worked long hours, with 55 working hours/week or more, have a higher risk of developing atrial fibrillation (AF) than those who worked standard hours (35–40 hours/week), according to a pooled analysis of data from the IPD-Work* Consortium.
Individuals who are married or report being very satisfied with life have a lower risk of developing mild cognitive impairment (MCI) and dementia, according to results from the Singapore Longitudinal Ageing Study (SLAS).
The predictors of further attacks in patients being treated for neuromyelitis optica spectrum disorder (NMOSD) are age, antibody status and possible previous attacks, according to recent study. Additionally, azathioprine and rituximab perform better than interferon-β in the treatment of NMOSD.
Transcatheter aortic valve replacement (TAVR) with a self-expanding prosthesis is noninferior to surgical aortic valve replacement (SAVR) in terms of death from any cause or disabling stroke at 2 years in intermediate-risk patients with severe aortic stenosis (AS), according to data from the SURTAVI* trial presented at the ACC.17 held in Washington, DC, US.
Individuals who underwent autologous haematopoietic stem cell transplantation (AHSCT) as a treatment for multiple sclerosis (MS) had improved progression-free survival (PFS) and overall survival (OS) five years post-transplant, a recent retrospective, observational study found.