Craniofacial abnormalities affect a significant proportion of society. Cleft lip and/or palate, for example, occurs in 1 per 500–700 births, depending on geography and ethnicity. The costs in terms of morbidity, psychological disturbance, and social and workplace exclusion are considerable for patients and their families, and society. The average incidence of new cleft cases is 2 clefts per 1,000 live births in the combined populations of Thailand, Bangladesh, Bhutan, Brunei, Cambodia, Indonesia, Laos, Malaysia, Nepal, Pakistan, Philippines, Singapore, Sri Lanka, and Vietnam.1
Cerebral palsy (CP) is one of the leading causes of childhood disability. It has been defined as ‘a disorder of movement and posture, causing activity limitation that is attributed to non-progressive disturbances that occurred in the developing fetal or infant brain’.
Individuals who are married or report being very satisfied with life have a lower risk of developing mild cognitive impairment (MCI) and dementia, according to results from the Singapore Longitudinal Ageing Study (SLAS).
The predictors of further attacks in patients being treated for neuromyelitis optica spectrum disorder (NMOSD) are age, antibody status and possible previous attacks, according to recent study. Additionally, azathioprine and rituximab perform better than interferon-β in the treatment of NMOSD.
Transcatheter aortic valve replacement (TAVR) with a self-expanding prosthesis is noninferior to surgical aortic valve replacement (SAVR) in terms of death from any cause or disabling stroke at 2 years in intermediate-risk patients with severe aortic stenosis (AS), according to data from the SURTAVI* trial presented at the ACC.17 held in Washington, DC, US.
Individuals who underwent autologous haematopoietic stem cell transplantation (AHSCT) as a treatment for multiple sclerosis (MS) had improved progression-free survival (PFS) and overall survival (OS) five years post-transplant, a recent retrospective, observational study found.