Top Medical News
Pearl Toh, Yesterday
Transcatheter aortic valve replacement (TAVR) with a self-expanding prosthesis is noninferior to surgical aortic valve replacement (SAVR) in terms of death from any cause or disabling stroke at 2 years in intermediate-risk patients with severe aortic stenosis (AS), according to data from the SURTAVI* trial presented at the ACC.17 held in Washington, DC, US.
Pearl Toh, 3 days ago
Intensive LDL lowering through the addition of the PCSK9* inhibitor evolocumab to statin therapy significantly reduced the risk of cardiovascular (CV) events in patients with existing atherosclerotic CV disease, according to data from the FOURIER** trial presented at the American College of Cardiology’s 66th Annual Scientific Session (ACC.17) held in Washington, DC, US.
Roshini Claire Anthony, 3 days ago
Individuals who are married or report being very satisfied with life have a lower risk of developing mild cognitive impairment (MCI) and dementia, according to results from the Singapore Longitudinal Ageing Study (SLAS). 
4 days ago
Despite their considerable similarities in terms of clinical features, attention deficit disorder (ADD) and neurofibromatosis type 1 (NF1) have important neurophysiological differences, particularly in perceptual categorization and response inhibition, a new study shows.
5 days ago
Obesity appears to have a negative effect on the potential of exercise-based motivational interviewing (MI) to improve symptom severity and pain in patients with fibromyalgia (FM), according to study.
5 days ago
There is a shortage of information comparing the efficacy of treatments for patients with highly active (HA) and rapidly evolving severe (RES) relapsing-remitting multiple sclerosis (RRMS), resulting in low-confidence conclusions, a new systematic literature review reveals.
Roshini Claire Anthony, 7 days ago

Individuals who underwent autologous haematopoietic stem cell transplantation (AHSCT) as a treatment for multiple sclerosis (MS) had improved progression-free survival (PFS) and overall survival (OS) five years post-transplant, a recent retrospective, observational study found.

Special Reports
Roshini Claire Anthony, 24 Jan 2017

Ocrelizumab, a humanized anti-CD20 monoclonal antibody, was associated with a reduced rate of disability progression in individuals with primary progressive multiple sclerosis (MS), based on findings of the phase III ORATORIO* trial.

Roshini Claire Anthony, 22 Nov 2016

Blood pressure lowering medications and statins do not prevent cognitive and functional decline in elderly patients, according to results of the HOPE-3 trial* presented at the Scientific Sessions of the American Heart Association (AHA 2016) held recently in New Orleans, Louisiana, US.

Dr. Rose Zhao-Wei Ting, 16 Nov 2016
A 55-year-old man presented with almost one year history of heat intolerance, mild palpitation and significant weight loss. Free T3 and T4 were elevated with normal TSH. Patient had suboptimal response to carbimazole therapy.
24 Aug 2016

Roshini Claire Anthony spoke with Adjunct Associate Professor Gamaliel Tan, head and senior orthopaedic consultant at Ng Teng Fong Hospital in Singapore, on how GPs can help diagnose and treat lower back pain.

29 Apr 2016
This article presents the excerpts from the Inaugural Meeting of the Dementia Advisory Board Malaysia held on 23 January 2016 in Kuala Lumpur, highlighting the clinical evidence of Ginkgo biloba extract EGb761® in dementia, treatment recommendations from international guidelines and consensus reached during the meeting on the role of EGb761® in managing dementia.
22 Apr 2016
Painful diabetic neuropathy (PDN) is one of the many complications of diabetes. At the Diabetes Asia 2015 Conference, renowned speaker Dr Mary Cardosa gave an overview on PDN and the approaches to managing this condition.
03 Mar 2016
The Drug Control Authority (DCA) of Malaysia has approved a new indication for the long-acting somatostatin analogue lanreotide. This new indication is for the treatment of grade 1 and low grade 2 gastroenteropancreatic neuroendocrine tumours (GEP-NETs)—of midgut, pancreatic or unknown origin except the hindgut—in adult patients with unresectable locally advanced or metastatic disease.
Conference Reports
Pearl Toh, 23 Mar 2017
Transcatheter aortic valve replacement (TAVR) with a self-expanding prosthesis is noninferior to surgical aortic valve replacement (SAVR) in terms of death from any cause or disabling stroke at 2 years in intermediate-risk patients with severe aortic stenosis (AS), according to data from the SURTAVI* trial presented at the ACC.17 held in Washington, DC, US.
Pearl Toh, 21 Mar 2017
Intensive LDL lowering through the addition of the PCSK9* inhibitor evolocumab to statin therapy significantly reduced the risk of cardiovascular (CV) events in patients with existing atherosclerotic CV disease, according to data from the FOURIER** trial presented at the American College of Cardiology’s 66th Annual Scientific Session (ACC.17) held in Washington, DC, US.
Pearl Toh, 10 Mar 2017
Contact aspiration is comparable to stent retriever (SR) as frontline thrombectomy for patients with acute ischaemic stroke resulting from large vessel occlusion (LVO), according to the ASTER* trial presented at the recent International Stroke Conference (ISC 2017) held in Texas, Houston, US.
Roshini Claire Anthony, 09 Mar 2017

The phosphodiesterase 3 inhibitor cilostazol may prevent secondary stroke in individuals with a recent history of ischaemic stroke. However, there was a higher incidence of myocardial infarction in this group, according to findings of the PICASSO* study presented at the International Stroke Conference 2017 (ISC 2017) in Houston, Texas, US.

Roshini Claire Anthony, 08 Mar 2017

Initiating statin therapy within 24 hours of hospitalization for an acute ischaemic stroke did not appear to affect patient disability at 90 days poststroke, according to findings of the ASSORT* trial presented at the International Stroke Conference 2017 (ISC 2017) in Houston, Texas, US.

Roshini Claire Anthony, 07 Mar 2017

Intensive (triple) antiplatelet therapy does not affect the recurrence of ischaemic stroke or transient ischaemic attack (TIA) compared with guideline standard-of-care antiplatelet therapy, but increases the risk of bleeding, according to interim data from the TARDIS* trial presented at the International Stroke Conference 2017 (ISC 2017) in Houston, Texas.

Roshini Claire Anthony, 03 Mar 2017

Resuming oral anticoagulation therapy after a lobar or nonlobar intracerebral haemorrhage (ICH) is associated with a lower risk of mortality and favourable functional outcome, according to results of a meta-analysis presented at the International Stroke Conference 2017 (ISC 2017) in Houston, Texas, US.