Sleep disorders commonly occur in patients with ankylosing spondylitis (AS), particularly those with high disease activity, a study has found. Furthermore, treatment with antitumour necrosis factor (anti-TNF)-α improves sleep quality but not polysomnography parameters.
Targeting mast cells with imatinib, which inhibits the receptor tyrosine kinase KIT, may decrease airway hyperresponsiveness and improve symptoms in patients with severe, poorly controlled asthma, according to a proof-of-principle clinical trial.
The risk of respiratory syncytial virus hospitalization (RSVH) and respiratory-related illness hospitalization (RIH) does not significantly differ between the first and second year of life in paediatric patients with haemodynamically significant congenital heart disease (HSCHD), a new study shows.
A combination of aerobic and resistance exercise training during weight loss yields the greatest improvement in physical function and reduction of frailty, with relative preservation of lean mass, in older adults with obesity as compared with participation in either exercise training programme alone, according to a study.
The fully-human immunocytokine dekavil (also known as F8-IL10) has demonstrated signs of safety and efficacy in patients with active rheumatoid arthritis (RA) in a phase I study presented at the European League Against Rheumatism (EULAR) Annual Congress 2017.
It appears that the use of bioresorbable vascular scaffolds (BVS) in patients undergoing percutaneous coronary intervention is linked to higher thrombotic risk and reduced efficacy over time compared with metallic everolimus-eluting stents (EES), a recent study suggests.
The risk of cardiovascular morbidity is reduced in elderly patients who highly adhere to antihypertensive drug therapy, reports a new study. Furthermore, adherence to antihypertensives also lowers the risk of heart failure and stroke, but not myocardial infarction (MI), and extending to all-cause death.
Statins appear to have a dose-dependent association with the risk of tuberculosis (TB), with a nationwide population-based study showing that statin users have 47 percent lower incidence of TB compared with nonusers.
At a recent lunch symposium during the 14th Annual Scientific Meeting of the Malaysian Society of Hypertension, Dr Chow Yok Wai spoke on the importance of patient adherence in the management of hypertension, highlighting the role of combination therapy in improving treatment outcomes.
Individuals with high fasting plasma glucose (FPG) lost more weight than those who had low FPG in response to a high-fibre, low glycaemic load diet, suggesting that FPG could be used as a biomarker to predict dietary weight loss success and to guide selection of the most effective diet, in particular for those with prediabetes and diabetes, according to studies presented at ADA 2017.