The implementation of point-of-care testing (POCT) for viral respiratory infections in emergency departments could reduce unnecessary hospitalizations and antibiotic treatment, according to a study from the UK.
The use of the anti-interleukin-4 receptor α monoclonal antibody dupilumab led to improved patient-reported and sino-nasal outcomes in asthma patients with chronic rhinosinusitis with or without nasal polyposis (CRS/NP), a common comorbidity of asthma, according to two prespecified analyses results of the LIBERTY ASTHMA QUEST* trial presented at ERS 2018.
Individuals with asthma may have a tendency to develop obesity, with a higher risk observed among those with adult-onset asthma, according to findings of the European Community Respiratory Health Survey (ECRHS) presented at the recent international congress of the European Respiratory Society (ERS 2018).
Triple therapy with budesonide, glycopyrrolate, and formoterol in one metered dose inhaler (BGF MDI) appears effective and is well-tolerated in patients with symptomatic moderate-to-severe chronic obstructive pulmonary disease (COPD) irrespective of exacerbation history, the multicentre, phase III KRONOS* trial has shown.
The airway microbiota is recently demonstrated to be associated with lung cancer via up-regulation of the ERK, PI3K and IL-17A signalling pathways, according to data presented at the recent European Respiratory Society (ERS) International Congress 2018.
Adding targeted lung denervation to drug therapy more than halves the rate of adverse respiratory events compared with drug therapy alone in patients with persistent chronic obstructive pulmonary disease (COPD), according to the AIRFLOW*-2 trial presented at ERS 2018.
Multidisciplinary discussions, connective tissue disease (CTD) screening and the performance of bronchoalveolar lavage (BAL) are among the pivotal points recommended by new guidelines for the diagnosis of idiopathic pulmonary fibrosis (IPF) reported at the recent European Respiratory Society (ERS) International Congress 2018.
Preterm infants who tested positive for ureaplasma respiratory tract infection had poorer survival over the first year of life, according to a study presented at ERS 2018. However, a 3-day course of prophylactic azithromycin could potentially reduce this morbidity and mortality burden.
The interleukin-5 receptor alpha (IL-5Rα) antagonist benralizumab has demonstrated durable efficacy and safety among patients with severe, uncontrolled eosinophilic asthma in a study reported at the recent European Respiratory Society (ERS) International Congress 2018.
Long-term treatment with the anti–interleukin-5 (anti–IL-5) monoclonal antibody mepolizumab provides sustained reductions in exacerbation rate and daily oral corticosteroid (OCS) use in patients with life-threatening or seriously debilitating severe eosinophilic asthma (SEA), according to results of the COSMEX study reported at the European Respiratory Society (ERS) International Congress 2018.
Treatment with intravenous (IV) dexamethasone for 10 days significantly reduces duration of mechanical ventilation at 28 days and 60-day mortality in patients with established moderate-to-severe acute respiratory disease syndrome (ARDS) compared with no dexamethasone, results of the DEXA-ARDS trial have shown.