Top Medical News
Tristan Manalac, an hour ago
The rapidly growing elderly population of Singapore is a major risk factor contributing to the recent rise in tuberculosis (TB) cases in the country, a new study reveals. This may lead to further increases in incidence despite improving TB monitoring and management mechanisms.
Elvira Manzano, an hour ago
A new guideline on when to deprescribe proton pump inhibitors (PPIs) in the setting of gastroesophageal reflux disease (GERD) and other upper gastrointestinal (GI) symptoms will guide clinicians’ treatment decisions amid increasing concerns over PPI overuse.
3 hours ago
Anti-RNA polymerase III antibodies (anti-RNAP3)‒positive patients with systemic sclerosis (SSc) are at an increased risk of concomitant malignancy, reports a new study.
4 hours ago
Higher plasma percentages of ω-3 polyunsaturated fatty acids (PUFAs) and a lower ratio of ω-6-to-ω-3 PUFAs in the late-second trimester of pregnancy are predictors of less weight retention at 18 months postpartum, according to a study involving a multiethnic Asian cohort.
5 hours ago
Infants born to mothers who smoke while pregnant are at an increased risk of developing bone fractures at preschool age, with maternal smoking having a potential negative effect on the bone development of the foetus, a study suggests.
Stephen Padilla, 11 hours ago
It appears that prescribing immediate antibiotics does not lessen major adverse outcomes of subsequent hospital admission or death for young people and adults with uncomplicated lower respiratory tract infection, a recent study has shown.
11 hours ago
A low rate of metabolic clearance of insulin (MCRI) in nonobese, healthy Japanese males is correlated with increased adiposity, reduced fitness and defective insulin sensitivity of the muscles, a new study shows.
Special Reports
25 May 2017
At a recent lunch symposium during the 14th Annual Scientific Meeting of the Malaysian Society of Hypertension, Dr Chow Yok Wai spoke on the importance of patient adherence in the management of hypertension, highlighting the role of combination therapy in improving treatment outcomes.
Prof. Ignatius Ou Sai Hong, Dr. James Suh, Dr. Wong Seng Weng, Dr. Amit Verma, 14 May 2017
As targeted cancer therapy options are increasing, it is becoming more important to choose the most appropriate treatment for patients with cancer. At a Roche-sponsored symposium held during the 2nd ESMO Asia Congress in Singapore, four experts discussed the potential of comprehensive genomic profiling (CGP) for personalizing cancer care and helping healthcare professionals to make the best treatment decisions for individual patients.
05 May 2017
At a recent satellite symposium convened during the 11th Asian & Oceanian Epilepsy Congress (AOEC) in Hong Kong, experts on convulsive epilepsy discussed the dilemmas and challenges currently encountered in the diagnosis and subsequent management of generalized tonic-clonic (GTC) seizures. The symposium was chaired by Dr Ada Yung (Associate Consultant, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Hong Kong), and it focused in particular on perampanel, the first and only approved non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor antagonist. Perampanel is approved for the management of patients experiencing partial-onset seizures, with or without secondarily generalized seizures, in seven countries across Asia and for primary GTC seizures in four Asian countries, with more approvals expected later this year.
28 Apr 2017
Idiopathic pulmonary fibrosis (IPF) is a disease marked by scarring and hardening of lung tissues. As a result, the lungs are unable to take in oxygen normally, which leads to lack of oxygen in the bloodstream, causing functional impairment and disability.1 Respiratory medicine experts, Professor Dr Paul W. Noble and Professor Dr Liam Chong Kin recently spoke to MIMS Doctor on IPF diagnosis and treatment. Here are the highlights from the interview.
24 Apr 2017
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to treat pain and inflammation in patients with arthritis, but the vascular effects of some NSAIDs have cast doubt on whether they can be used in patients at risk for cardiovascular (CV) disease. At the American Heart Association’s Scientific Sessions 2016 held recently in New Orleans, Louisiana, US, Professor Steven Nissen of the Cleveland Clinic in Cleveland, Ohio, US, presented latest data from the PRECISION (Prospective Randomized Evaluation of Celecoxib Integrated Safety vs Ibuprofen or Naproxen) trial that evaluated the CV risk and safety profile of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib vs nonselective NSAIDs.
12 Apr 2017
CANESTEN HC – Clotrimazole 1% w/w and hydrocortisone 1% w/w cream – Bayer
12 Apr 2017
ESBRIET – Pirfenidone 267 mg hard cap – Roche
Conference Reports
Audrey Abella, 12 May 2017
Identifying which type of patient would benefit from a particular crystalloid is essential in intravenous (IV) fluid therapy, according to a presentation at the 4th SG-ANZICS Intensive Care Forum 2017 held in Singapore.
Christina Lau, 10 May 2017

The use of granulocyte colony stimulating-factor (G-CSF) is safe in patients with limited-stage small-cell lung cancer (SCLC) treated with chemoradiotherapy, according to a post hoc analysis of the phase III CONVERT trial presented at the European Lung Cancer Conference (ELCC) 2017.

Christina Lau, 09 May 2017

Ensartinib, a small-molecule ALK tyrosine kinase inhibitor (TKI), has demonstrated intracranial response in patients with ALK-positive non-small-cell lung cancer (NSCLC) with central nervous system (CNS) metastases.

Christina Lau, 09 May 2017

Treatment with osimertinib significantly improves symptoms in patients with advanced non-small-cell lung cancer (NSCLC), according to new data from the phase III AURA3 trial presented at the European Lung Cancer Conference (ELCC) 2017.

Christina Lau, 09 May 2017

Patients treated with PD-1/PD-L1 checkpoint inhibitors may be at increased risk of immune-related adverse events (irAEs) after receiving seasonal influenza vaccination, a small study presented at the European Lung Cancer Conference (ELCC) 2017 has shown.

Elvira Manzano, 04 May 2017
Malnutrition, as assessed by a simple nutrition-screening tool, is independently associated with hospital mortality among ICU patients, according to a Singapore cohort study and a meta-analysis.
Pearl Toh, 03 May 2017
Bed strain in intensive care unit (ICU) can significantly affect patient outcomes, in particular mortality, but increasing the number of beds available does not help solve the issues faced in a strained ICU, according to a presentation at the recent SG- SG-ANZICS Intensive Care Forum (SG-ANZICS 2017) in Singapore.
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