Top Medical News
Stephen Padilla, 3 hours ago
Patients receiving chlorthalidone are less likely to develop treatment-resistant hypertension compared with those receiving amlodipine or lisinopril, according to a study that titrated medications to a goal. However, the risk of cardiovascular outcomes remains similar for patients with treatment-resistant hypertension across all three therapy groups.
4 hours ago
Patients with diabetic macula oedema (DME) slow down the development of proliferative diabetic retinopathy (PDR) and progression of DR with sustained intraocular delivery of fluocinolone acetonide (FAc), a recent study shows.
10 hours ago
Hypogonadal men with type 2 diabetes are highly likely to have higher bone mass density (BMD), poorer bone geometry and relatively suppressed bone turnover compared with their nondiabetic counterparts, a study has shown.
14 hours ago
Magnesium-aluminium antacid gel and alginate-based reflux suppressant have comparable efficacies in treating heartburn in pregnancy, a new study shows.
18 hours ago
Beta-blocker therapy appears to play an important role in the prevention of cardiac events during pregnancy and the postpartum period in patients with long QT syndrome (LQTS), according to a study, with beta-blockers having no adverse effect on foetal growth.
22 hours ago
Hypertension is associated with an increased risk of breast cancer, particularly among postmenopausal women, a new meta-analysis finds.
Siblings of men with oligozoospermia are susceptible to any-site cancer and acute lymphoblastic leukaemia, according to a recent study.
Special Reports
20 Mar 2017
At the recent Asian Pacific Digestive Week (APDW) 2016 held in Kobe, Japan, three prominent international experts shared their views on gastroesophageal reflux disease (GERD) and the challenges of its management.
20 Mar 2017
At a recent lunch satellite symposium held in conjunction with the Malaysian Society of Anaesthesiologists & College of Anaesthesiologists Annual Scientific Congress 2016, Dr Choo Chee Yong talked about the current perspectives and clinical uses of oxycodone in managing postoperative pain.
17 Mar 2017
On 6 November 2016, in conjunction with the first year anniversary of vortioxetine (Brintellix®, Lundbeck) in Malaysia, two distinguished speakers, Professor Gin S Malhi and Dr Pranab Kalita shared updates on depression and the use of vortioxetine in order to help patients with major depressive disorders (MDD) to return to their premorbid functional states. The session was followed by three case presentations.
16 Mar 2017
Recently, Dr Peter Lin of the Canadian Heart Research Centre spoke on treatment strategies in the management of dyslipidaemia and T2DM at an AstraZeneca-sponsored continuing medical education event. Highlights of his presentations are summarized below.
13 Mar 2017
With the drive to share the current healthcare expert’s practices in managing different types of infections, Mundipharma conducted its 1st PLUS (Pharmacy cLinical UpdateS) Summit by inviting a group of consultants to share the role of povidone-iodine (PVP-I) in infection prevention and management with the community pharmacists on 15th–16th October 2016 in Port Dickson.
07 Mar 2017
At the 17th Malaysian Society of Rheumatology/Singapore Society of Rheumatology Workshop, Associate Professor Susanna Proudman, a senior consultant in rheumatology from Australia, shared with the audience on the diagnosis and management of pulmonary arterial hypertension (PAH), with a focus on systemic sclerosis (SSc)-related PAH.
01 Mar 2017
At the recent Asia Pacific Alliance for the Control of Influenza (APACI) workshop in Kuala Lumpur, MIMS Doctor had the privilege of having an exclusive interview with eminent paediatric infectious disease specialist, Associate Professor Tawee Chotpitayasunondh. This article captures the highlights from our conversation with him.
Conference Reports
Pearl Toh, 25 Mar 2017
Treatment with inclisiran, a siRNA for PCSK9 knockdown, delivers significant and sustained LDL-C lowering in a dose-dependent manner over 6 to 9 months in patients with high cardiovascular (CV) risk, according to the ORION-1* study presented at the ACC.17 Scientific Session held in Washington, DC, US.
Roshini Claire Anthony, 24 Mar 2017

Patients with atrial fibrillation (AF) given digoxin appear to have an elevated risk of mortality, regardless of whether or not they have heart failure, according to a post hoc analysis of the ARISTOTLE* trial presented at the American College of Cardiology (ACC) 66th Scientific Session in Washington DC, US. 

Audrey Abella, 24 Mar 2017
Anticoagulants (ie, novel oral anticoagulants [NOACs], warfarin) were effective in treating subclinical leaflet thrombosis after aortic valve replacement (AVR) compared with dual antiplatelet therapy (DAPT) or mono-antiplatelet therapy (MAPT), according to data presented at the American College of Cardiology’s (ACC) 66th Annual Scientific Session, held in Washington, DC, US.
Audrey Abella, 24 Mar 2017
Adding low-dose rivaroxaban to ticagrelor or clopidogrel did not result in major bleeding complications in patients with acute coronary syndrome (ACS) compared with patients on standard dual antiplatelet therapy (DAPT) of aspirin plus antiplatelet, according to the GEMINI-ACS-1* trial.
Pearl Toh, 23 Mar 2017
Transcatheter aortic valve replacement (TAVR) with a self-expanding prosthesis is noninferior to surgical aortic valve replacement (SAVR) in terms of death from any cause or disabling stroke at 2 years in intermediate-risk patients with severe aortic stenosis (AS), according to data from the SURTAVI* trial presented at the ACC.17 held in Washington, DC, US.
Audrey Abella, 22 Mar 2017
Fractional flow reserve (FFR)-guided complete revascularization of non-infarct-related arteries in acute primary percutaneous coronary intervention (PCI) reduced the risk of cardiovascular outcomes compared with treating infarct-related arteries (IRA) only, according to the Compare-Acute* trial presented at the American College of Cardiology’s (ACC) 66th Annual Scientific Session held in Washington, DC, US.
Roshini Claire Anthony, 21 Mar 2017

Prophylactic infusion of levosimendan did not reduce death or perioperative myocardial infarction or the need for dialysis or mechanical cardiac assist device more than placebo in patients at risk for low cardiac output syndrome undergoing cardiac bypass. However, it increased cardiac output and reduced low cardiac output syndrome, according to primary findings of the LEVO-CTS* trial. 

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