Top Medical News
Tristan Manalac, 4 hours ago
Mechanical stimulation of ex vivo human skin explants at around 75 Hz increases expression of structural dermal and dermal-epidermal junction (DEJ) proteins. In vivo, mechanical stimulation enhances the anti-ageing effects of an anti-aging cream, a new study shows.
8 hours ago
Sodium glucose co-transport-2 (SGLT-2) inhibitors show potential therapeutic value when used as an adjunct to insulin in the management of type 1 diabetes mellitus (T1DM), according to a meta-analysis. The use of SGLT-2 inhibitors appears to effectively improve glycaemic control, reduce body weight and total daily insulin dose without increasing adverse events, as well as lower the incidence of hypoglycaemia or genital and urinary infections.
Stephen Padilla, 12 hours ago
Using a novel mobile digital platform is feasible for data collection and management in low-resource settings, a pilot study shows. Furthermore, there is high user satisfaction primarily due to improved operational efficiencies and data quality processes.
13 hours ago
The combination of corticosteroid and pentoxifylline shows noninferiority to corticosteroid monotherapy in severe alcoholic hepatitis and may attenuate the incidence of hepatorenal syndrome or acute kidney injury and risk of infection, suggests a study.
14 hours ago
The quality of care for patients with serious mental illness and cardiovascular risk factors can be improved even under challenging real-world conditions, suggest a recent study.
20 hours ago
There has been a substantial increase in the rate of midazolam utilization for benzodiazepine-treated seizures following the publication of data from Rapid Anticonvulsant Medication Prior to Arrival Trial (RAMPART), according a new observational study. Furthermore, the safety and efficacy of midazolam in the prehospital setting in clinical practice appear consistent with the RAMPART data.
Roshini Claire Anthony, Yesterday

Survivors of Hodgkin lymphoma (HL) have a twofold risk of developing a second cancer, with a higher risk among those with a family history of cancer, a recent study found.

Special Reports
20 Mar 2017
At the recent Asian Pacific Digestive Week (APDW) 2016 held in Kobe, Japan, three prominent international experts shared their views on gastroesophageal reflux disease (GERD) and the challenges of its management.
20 Mar 2017
At a recent lunch satellite symposium held in conjunction with the Malaysian Society of Anaesthesiologists & College of Anaesthesiologists Annual Scientific Congress 2016, Dr Choo Chee Yong talked about the current perspectives and clinical uses of oxycodone in managing postoperative pain.
17 Mar 2017
On 6 November 2016, in conjunction with the first year anniversary of vortioxetine (Brintellix®, Lundbeck) in Malaysia, two distinguished speakers, Professor Gin S Malhi and Dr Pranab Kalita shared updates on depression and the use of vortioxetine in order to help patients with major depressive disorders (MDD) to return to their premorbid functional states. The session was followed by three case presentations.
16 Mar 2017
Recently, Dr Peter Lin of the Canadian Heart Research Centre spoke on treatment strategies in the management of dyslipidaemia and T2DM at an AstraZeneca-sponsored continuing medical education event. Highlights of his presentations are summarized below.
13 Mar 2017
With the drive to share the current healthcare expert’s practices in managing different types of infections, Mundipharma conducted its 1st PLUS (Pharmacy cLinical UpdateS) Summit by inviting a group of consultants to share the role of povidone-iodine (PVP-I) in infection prevention and management with the community pharmacists on 15th–16th October 2016 in Port Dickson.
07 Mar 2017
At the 17th Malaysian Society of Rheumatology/Singapore Society of Rheumatology Workshop, Associate Professor Susanna Proudman, a senior consultant in rheumatology from Australia, shared with the audience on the diagnosis and management of pulmonary arterial hypertension (PAH), with a focus on systemic sclerosis (SSc)-related PAH.
01 Mar 2017
At the recent Asia Pacific Alliance for the Control of Influenza (APACI) workshop in Kuala Lumpur, MIMS Doctor had the privilege of having an exclusive interview with eminent paediatric infectious disease specialist, Associate Professor Tawee Chotpitayasunondh. This article captures the highlights from our conversation with him.
Conference Reports
Pearl Toh, 23 Mar 2017
Transcatheter aortic valve replacement (TAVR) with a self-expanding prosthesis is noninferior to surgical aortic valve replacement (SAVR) in terms of death from any cause or disabling stroke at 2 years in intermediate-risk patients with severe aortic stenosis (AS), according to data from the SURTAVI* trial presented at the ACC.17 held in Washington, DC, US.
Audrey Abella, 22 Mar 2017
Fractional flow reserve (FFR)-guided complete revascularization of non-infarct-related arteries in acute primary percutaneous coronary intervention (PCI) reduced the risk of cardiovascular outcomes compared with treating infarct-related arteries (IRA) only, according to the Compare-Acute* trial presented at the American College of Cardiology’s (ACC) 66th Annual Scientific Session held in Washington, DC, US.
Roshini Claire Anthony, 21 Mar 2017

Prophylactic infusion of levosimendan did not reduce death or perioperative myocardial infarction or the need for dialysis or mechanical cardiac assist device more than placebo in patients at risk for low cardiac output syndrome undergoing cardiac bypass. However, it increased cardiac output and reduced low cardiac output syndrome, according to primary findings of the LEVO-CTS* trial. 

Pearl Toh, 21 Mar 2017
Intensive LDL lowering through the addition of the PCSK9* inhibitor evolocumab to statin therapy significantly reduced the risk of cardiovascular (CV) events in patients with existing atherosclerotic CV disease, according to data from the FOURIER** trial presented at the American College of Cardiology’s 66th Annual Scientific Session (ACC.17) held in Washington, DC, US.
Dr. Angela V. Ignacio, 20 Mar 2017
Obstructive sleep apnoea (OSA) and central sleep apnoea (CSA) appear to occur in nearly half and one-tenth of patients with acute myocardial infarction (AMI), respectively, and may resolve or change from one type to another in the 6 months following AMI, according to results of a Singaporean study presented at the American College of Cardiology’s 66th Annual Scientific Session in Washington, D.C.
Dr. Angela V. Ignacio, 20 Mar 2017
Among breast cancer survivors, engaging in high levels of physical activity before or around the time of diagnosis may decrease the risk of developing cardiovascular events (CVE) and dying from coronary heart disease (CHD) after receiving cancer therapy, according to a study presented at the American College of Cardiology’s 66th Annual Scientific Session in Washington, DC.
Pearl Toh, 13 Mar 2017
Pearl Toh finds out from Professor Anna Lok, director of clinical hepatology at the University of Michigan in Ann Arbor, Michigan, US, on integrating guidelines, research data, and clinical setting in decision making for management of hepatitis B during the recent Asian Pacific Association for the Study of the Liver Annual Meeting held in Shanghai, China.

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